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TNP1 gene

Known as: TRANSITION PROTEIN 1, Transition Protein 1 (During Histone to Protamine Replacement) Gene, TNP1 
This gene is involved in spermatid maturation.
National Institutes of Health

Related topics

Related topics

3 relations
Single Strand Break RepairSpermatogenesistransition protein 1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Five Different Piscidins from Nile Tilapia, Oreochromis niloticus: Analysis of Their Expressions and Biological Functions
Piscidins are antimicrobial peptides (AMPs) that play important roles in helping fish resist pathogenic infections. Through… 
Highly Cited
2006
Highly Cited
2006
Identification of novel polymorphisms in the nuclear protein genes and their relationship with human sperm protamine deficiency and severe male infertility.
Highly Cited
2005
Highly Cited
2005
Single-nucleotide polymorphisms and mutation analyses of the TNP1 and TNP2 genes of fertile and infertile human male populations.
Previously, we examined the relationship between protamine gene variations and human male infertility. In this study, we show… 
Highly Cited
2004
Highly Cited
2004
Transition nuclear proteins are required for normal chromatin condensation and functional sperm development
Summary: The histone‐to‐protamine transition is important in the formation of spermatozoa. In mammals this involves two steps… 
Highly Cited
1994
Highly Cited
1994
Identification of a functional cyclic adenosine 3',5'-monophosphate response element in the 5'-flanking region of the gene for transition protein 1 (TP1), a basic chromosomal protein of mammalian…
Transition protein 1 (TP1) is a small basic chromosomal protein that appears in mammalian spermatids during the period of… 
Highly Cited
1991
Highly Cited
1991
Cytoplasmic localization during storage and translation of the mRNAs of transition protein 1 and protamine 1, two translationally regulated transcripts of the mammalian testis.
During spermatogenesis in mammals, the transcripts of transition protein 1 (TP 1) and protamine 1 (Prm 1) are under translational… 
Highly Cited
1989
Highly Cited
1989
Nucleotide sequence of the Stp-1 gene coding for rat spermatid nuclear transition protein 1 (TP1): homology with protamine P1 and assignment of the mouse Stp-1 gene to chromosome 1.
1989
1989
Nucleotide sequences and expression of cDNA clones for boar and bull transition protein 1 and its evolutionary conservation in mammals.
During spermatogenesis, the nucleoproteins undergo several dramatic changes as the germinal cells differentiate to produce the… 
Highly Cited
1988
Highly Cited
1988
A cytochemical study of the transcriptional and translational regulation of nuclear transition protein 1 (TP1), a major chromosomal protein of mammalian spermatids
Immunocytochemical localization and in situ hybridization techniques were used to investigate the presence of spermatid nuclear… 
Highly Cited
1988
Highly Cited
1988
A non–cell–autonomous mutation regulating juvenility in maize
The transition from a juvenile to an adult phase of shoot growth in plants involves coordinated changes in a large number of… 
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