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TNFRSF11B protein, human

Known as: TNFRSF11B, osteoprotegerin protein, human, TR1 protein, human 
Tumor necrosis factor receptor superfamily member 11B (401 aa, ~46 kDa) is encoded by the human TNFRSF11B gene. This protein plays a role in the… 
National Institutes of Health

Related topics

Related topics

18 relations
ApoptosisApoptosis Regulatory ProteinsBTF3P11 geneCytokine Receptor Gene

Broader (1)

Tumor necrosis factor receptor 11b

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Osteoprotegerin Inactivation Accelerates Advanced Atherosclerotic Lesion Progression and Calcification in Older ApoE−/− Mice
Objective—Osteoprotegerin (OPG), a member of the tumor necrosis factor (TNF) superfamily of proteins, plays an important role in… 
Highly Cited
2001
Highly Cited
2001
The Effect of a Single Dose of Osteoprotegerin in Postmenopausal Women
Osteoprotegerin (OPG), a tumor necrosis factor (TNF) receptor family member, is a critical regulator of bone resorption. It is an… 
Highly Cited
2000
Highly Cited
2000
Osteoprotegerin produced by osteoblasts is an important regulator in osteoclast development and function.
Osteoprotegerin (OPG), a soluble decoy receptor for receptor activator of nuclear factor-kappaB ligand (RANKL)/osteoclast… 
Highly Cited
2000
Highly Cited
2000
Osteoprotegerin ligand modulates murine osteoclast survival in vitro and in vivo.
Highly Cited
1999
Highly Cited
1999
Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand.
A receptor that mediates osteoprotegerin ligand (OPGL)-induced osteoclast differentiation and activation has been identified via… 
Highly Cited
1999
Highly Cited
1999
Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand
Bone remodelling and bone loss are controlled by a balance between the tumour necrosis factor family molecule osteoprotegerin… 
Highly Cited
1999
Highly Cited
1999
The Ligand for Osteoprotegerin (OPGL) Directly Activates Mature Osteoclasts
Osteoprotegerin (OPG) and OPG-ligand (OPGL) potently inhibit and stimulate, respectively, osteoclast differentiation (Simonet, W… 
Highly Cited
1999
Highly Cited
1999
Estrogen stimulates gene expression and protein production of osteoprotegerin in human osteoblastic cells.
The identity of the paracrine mediator(s) of the antiresorptive action of estrogen on bone cells is controversial… 
Review
1999
Review
1999
A new member of tumor necrosis factor ligand family, ODF/OPGL/TRANCE/RANKL, regulates osteoclast differentiation and function.
Osteoclasts, the multinucleated giant cells that resorb bone, develop from monocyte-macrophage lineage cells. Osteoblasts or bone… 
Highly Cited
1999
Highly Cited
1999
Stimulation of Osteoprotegerin Ligand and Inhibition of Osteoprotegerin Production by Glucocorticoids in Human Osteoblastic Lineage Cells: Potential Paracrine Mechanisms of Glucocorticoid-Induced…
Osteoporosis is a serious complication of systemic glucocorticoid use. However, while glucocorticoids increase bone resorption in… 
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