TNFRSF10B protein, human

Known as: Tumor Necrosis Factor Receptor-Like Protein ZTNFR9, P53-Regulated DNA Damage-Inducible Cell Death Receptor (Killer), TRAILR2 
A protein on the surface of certain cells that binds another protein called TRAIL, which may kill some cancer cells. An increase in the amount or… (More)
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
The proteasome inhibitor PS-341 (bortezomib or Velcade), an approved drug for treatment of patients with multiple myeloma, is… (More)
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Highly Cited
2005
Highly Cited
2005
Curcumin exhibits anti-inflammatory and antitumor activities. Although its functional mechanism has not been elucidated so far… (More)
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Highly Cited
2005
Highly Cited
2005
Combined treatment with a proteasome inhibitor and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a promising… (More)
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Highly Cited
2004
Highly Cited
2004
Death receptor 5 (DR5) is a receptor for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). TRAIL is a promising… (More)
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Highly Cited
2004
Highly Cited
2004
Because tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) preferentially induces apoptosis in tumor cells and plays… (More)
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Highly Cited
2004
Highly Cited
2004
Bile acids up-regulate death receptor 5 (DR5)/TRAIL-receptor 2 (TRAIL-R2) expression thereby sensitizing hepatocytes to TRAIL… (More)
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Highly Cited
2001
Highly Cited
2001
Multiple myeloma (MM) remains incurable and novel treatments are urgently needed. Preclinical in vitro and in vivo evaluations… (More)
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Highly Cited
2000
Highly Cited
2000
The intractability of malignant gliomas to multimodality treatments plays a large part in their extremely poor prognosis. Tumor… (More)
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Highly Cited
2000
Highly Cited
2000
TRAIL is a member of the tumor necrosis factor (TNF) family of cytokines which induces apoptotic cell death in a variety of tumor… (More)
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Highly Cited
1999
Highly Cited
1999
TRAIL, an apoptosis inducing ligand, has at least four cell surface receptors including the death receptor DR5. Here we report… (More)
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