TNF-related apoptosis-inducing ligand

Known as: TNF Related Apoptosis Inducing Ligand, tumor necrosis factor-related apoptosis-inducing ligand, TNF Superfamily, Member 10 
A transmembrane-protein belonging to the TNF family of intercellular signaling proteins. It is a widely expressed ligand that activates APOPTOSIS by… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Adipose-derived mesenchymal stromal/stem cells (AD-MSC) may offer efficient tools for cell-based gene therapy approaches. In this… (More)
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Highly Cited
2007
Highly Cited
2007
PURPOSE To assess the safety, pharmacokinetics, and preliminary evidence of antitumor activity of mapatumumab (HGS-ETR1, TRM-1… (More)
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Review
2005
Review
2005
The tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is regarded as a potential anticancer agent. However… (More)
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Highly Cited
2005
Highly Cited
2005
Death receptor 5 (DR5/TRAIL-R2) is an apoptosis-inducing membrane receptor for tumor necrosis factor-related apoptosis-inducing… (More)
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Highly Cited
2004
Highly Cited
2004
Survivin is a member of the inhibitor of apoptosis proteins that is expressed at high levels in most human cancers and may… (More)
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Highly Cited
2003
Highly Cited
2003
Myeloma cells grow only in the bone marrow closely associated with bone,suggesting that this microenvironment provides critical… (More)
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Highly Cited
2002
Highly Cited
2002
A major concern in cancer therapy is resistance of tumors such as glioblastoma to current treatment protocols. Here, we report… (More)
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Highly Cited
2001
Highly Cited
2001
Apo2L/TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) is a member of the tumor necrosis factor gene family known… (More)
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Highly Cited
2000
Highly Cited
2000
The tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces apoptosis of tumor cells but not normal cells; its… (More)
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Highly Cited
1999
Highly Cited
1999
TNF and Fas ligand induce apoptosis in tumor cells; however, their severe toxicity toward normal tissues hampers their… (More)
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