TMPRSS2 protein, human

Known as: epitheliasin protein, human, transmembrane protease, serine 2 protein, human, EC 3.4.21.- 
Transmembrane protease serine 2 (492 aa, ~54 kDa) is encoded by the human TMPRSS2 gene. This protein plays a role in proteolysis.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
The novel human coronavirus EMC (hCoV-EMC), which recently emerged in Saudi Arabia, is highly pathogenic and could pose a… (More)
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Highly Cited
2011
Highly Cited
2011
More than 1,000,000 men undergo prostate biopsy each year in the United States, most for "elevated" serum prostate-specific… (More)
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2010
2010
The distribution of the severe acute respiratory syndrome coronavirus (SARS-CoV) receptor, an angiotensin-converting enzyme 2… (More)
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Highly Cited
2010
Highly Cited
2010
DNA double-strand breaks (DSBs) can lead to the development of genomic rearrangements, which are hallmarks of cancer. Fusions… (More)
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Highly Cited
2009
Highly Cited
2009
Hormone-driven expression of the ERG oncogene after fusion with TMPRSS2 occurs in 30% to 70% of therapy-naive prostate cancers… (More)
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2008
2008
Human metapneumovirus (HMPV) is a major causative agent of severe bronchiolitis and pneumonia. Its fusion (F) protein must be… (More)
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Highly Cited
2006
Highly Cited
2006
Host cell proteases that cleave the hemagglutinin (HA) of influenza viruses in the human respiratory tract are still not… (More)
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Highly Cited
2002
Highly Cited
2002
The epithelial sodium channel (ENaC) constitutes the rate-limiting step for sodium absorption across airway epithelia, which in… (More)
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2001
2001
The serine protease TMPRSS2 gene expression was studied by in situ hybridization using benign prostatic hyperplasia and prostate… (More)
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Highly Cited
1999
Highly Cited
1999
Genes regulated by androgenic hormones are of critical importance for the normal physiological function of the human prostate… (More)
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