TMEM67 gene

Ciliopathies are a group of developmental disorders that manifest with multi-organ anomalies. Mutations in TMEM67 (MKS3) cause a… (More)

Rotifer resting eggs often have to endure harsh environmental conditions during the diapause phase. They are stimulated by light… (More)

PURPOSE Cilia, complex structures found ubiquitously in most vertebrate cells, serve a variety of functions ranging from cell and… (More)

Defects in primary cilia structure or function result in both common and rare ciliopathies. We have characterized an ovine model… (More)

The dysfunction of the primary cilium, a complex, evolutionarily conserved, organelle playing an important role in sensing and… (More)

Meckel syndrome (MKS) is an embryonic lethal, autosomal recessive disorder characterized by polycystic kidney disease, central… (More)

Joubert syndrome (JBTS), related disorders (JSRDs) and Meckel syndrome (MKS) are ciliopathies. We now report that MKS2 and CORS2… (More)

We have developed anti-Evc2 antibodies and show that Evc2 and Evc co-localise at the basal body and also in primary cilia. In… (More)

We have developed anti-Evc2 antibodies and show that Evc2 and Evc co-localise at the basal body and also in primary cilia. In… (More)

We have developed anti-Evc2 antibodies and show that Evc2 and Evc co-localise at the basal body and also in primary cilia. In… (More)