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TMEM106B gene

Known as: TMEM106B, FLJ11273, MGC33727 
 
National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
Progranulin (GRN) and TMEM106B are associated with several common neurodegenerative disorders including frontotemporal lobar… Expand
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Highly Cited
2014
Highly Cited
2014
TMEM106B is a major risk factor for frontotemporal lobar degeneration with TDP-43 pathology. TMEM106B localizes to lysosomes, but… Expand
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Highly Cited
2013
Highly Cited
2013
Haploinsufficiency of Progranulin (PGRN), a gene encoding a secreted glycoprotein, is a major cause of frontotemporal lobar… Expand
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Highly Cited
2013
Highly Cited
2013
Hexanucleotide repeat expansions in chromosome 9 open reading frame 72 (C9orf72) have recently been linked to frontotemporal… Expand
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Highly Cited
2012
Highly Cited
2012
Frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP) is a fatal neurodegenerative disease with no available… Expand
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Highly Cited
2012
Highly Cited
2012
Background: TMEM106B, a major risk factor for FTLD, is a protein of unknown function and cellular properties. Results: TMEM106B… Expand
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Highly Cited
2011
Highly Cited
2011
OBJECTIVE To test whether rs1990622 (TMEM106B) is associated with age at onset (AAO) in granulin (GRN) mutation carriers and with… Expand
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Highly Cited
2011
Highly Cited
2011
In a genome-wide association study of frontotemporal lobar degeneration with pathological inclusions of TAR DNA-binding protein… Expand
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Highly Cited
2010
Highly Cited
2010
Objectives: To determine whether TMEM106B single nucleotide polymorphisms (SNPs) are associated with frontotemporal lobar… Expand
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Highly Cited
2010
Highly Cited
2010
Frontotemporal lobar degeneration (FTLD) is the second most common cause of presenile dementia. The predominant neuropathology is… Expand
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