TLR8 wt Allele

Known as: Toll-Like Receptor 8 wt Allele, TLR8, CD288 
Human TLR8 wild-type allele is located within Xp22 and is approximately 17 kb in length. This allele, which encodes toll-like receptor 8 protein, is… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Toll-like receptor 7 (TLR7) and TLR8 recognize single-stranded RNA and initiate innate immune responses. Several synthetic… (More)
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Highly Cited
2009
Highly Cited
2009
Dendritic cell (DC) responses to extracellular self-DNA and self-RNA are prevented by the endosomal seclusion of nucleic acid… (More)
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Review
2008
Review
2008
Small-molecule agonists at Toll-like receptor 7 (TLR7) and TLR8 have sparked a vivid interest in cancer research owing to their… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Toll-like receptors (TLRs) are structurally and functionally related and play important roles in the innate and… (More)
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Highly Cited
2006
Highly Cited
2006
Synthetic immune response modifiers (IRM) such as imidazoquinolines can selectively activate human TLR7 or TLR8. Although these… (More)
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Highly Cited
2006
Highly Cited
2006
Toll receptors in Drosophila melanogaster function in morphogenesis and host defense. Mammalian orthologues of Toll, the Toll… (More)
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Highly Cited
2006
Highly Cited
2006
Toll-like receptors (TLRs) TLR1, TLR2, TLR4, and TLR6 are evolutionarily conserved, highly homologous, and localized to plasma… (More)
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Highly Cited
2005
Highly Cited
2005
Although TLR7 and TLR8 are phylogenetically and structurally related, their relative functions are largely unknown. The role of… (More)
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Highly Cited
2002
Highly Cited
2000
Highly Cited
2000
We describe three novel genes, encoding members of the Toll-like receptor (Tlr) family (TLR7, TLR8, and TLR9). These Tlr family… (More)
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