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TLR8 wt Allele

Known as: Toll-Like Receptor 8 wt Allele, TLR8, CD288 
Human TLR8 wild-type allele is located within Xp22 and is approximately 17 kb in length. This allele, which encodes toll-like receptor 8 protein, is… 
National Institutes of Health

Related topics

Related topics

7 relations
Immune responseLigand BindingReceptor SignalingTLR8 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Evaluation of Toll-Like Receptor Alteration in Intestinal Biopsies of Patients with Irritable Bowel Syndrome: A Systematic Review
Background: Irritable bowel syndrome (IBS) is a functional disorder with an unknown etiology. Some recent studies report the… 
2012
2012
IMO-8400, a novel TLR7, TLR8 and TLR9 antagonist, inhibits disease development in lupus-prone NZBW/F1 mice (119.12)
Several studies have implicated Toll-like receptors (TLRs) 7, 8 and 9 in the development and progression of lupus. We have… 
2012
2012
IMO-8400, a novel TLR7, TLR8 and TLR9 antagonist, inhibits disease development in mouse models of psoriasis (119.8)
Toll-like receptors (TLR) are involved in the pathogenesis of numerous autoimmune diseases, including psoriasis. The role of… 
2011
2011
Poly-Thymidine Oligonucleotides Mediate Activation of Murine Glial Cells Primarily Through TLR7, Not TLR8
The functional role of murine TLR8 in the inflammatory response of the central nervous system (CNS) remains unclear. Murine TLR8… 
2010
2010
Positive selection signatures in the TLR7 family
While adaptive immunity genes evolve rapidly under the influence of positive selection, innate immune system genes are known to… 
2010
2010
A major role for TLR8 in the recognition of vaccinia viral DNA by murine pDC
2009
2009
Cancer immunotherapeutic potential of novel small molecule TLR7 and TLR8 agonists
Toll-like receptor (TLR)-mediated signaling is proposed as an immunotherapeutic target against tumorigenesis. Natural killer (NK… 
Highly Cited
2008
Highly Cited
2008
The duck toll like receptor 7: genomic organization, expression and function.
2008
2008
CD14+ cells are required for IL-12 response in bovine blood mononuclear cells activated with Toll-like receptor (TLR) 7 and TLR8 ligands.
2007
2007
Synthetic imidazoquinolines potently and broadly activate the cellular immune response of patients with cutaneous T-cell lymphoma: synergy with interferon-gamma enhances production of interleukin-12.
Advanced cutaneous T-cell lymphoma (CTCL) is typically associated with a variety of profound defects of cellular immunity… 
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