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TK 117

Known as: TK-117 
National Institutes of Health

Related topics

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2 relations

Broader (1)

Floxuridine
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1988
1988
[In vivo distribution and activation of 5-FU--with special reference to biochemical modulation of intracellular metabolism].
5-FU is metabolized to FUTP and FdUMP in tumor cells and exhibits RNA- and DNA-directed cytotoxicity. Biochemical modulation of… 
1985
1985
[Clinical phase II study of TK-117 by Cooperative Study Group. Effects on gastric cancer].
A clinical phase II study of TK-117, one of the derivatives of FUDR, was performed in 18 patients with gastric cancer by our… 
1984
1984
[Chemical modification of anticancer agents from viewpoints of their pharmacokinetics].
Many derivatives modifying chemical structures have been synthesized from several drugs. These include following antibiotics… 
1982
1982
[Pharmacological and pharmacodynamic aspects of cancer chemotherapy, with special reference to 5-fluorouracil and its derivatives].
5-FU analogs being investigated in Japan are; 5-FU, FT, FD-1, HCFU, UFT, TAC-278, 5'-DFUR, FF-705, and TK-117. They exert… 
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