TJAP1 gene

Known as: tight junction associated protein 1, TJP4, PROTEIN INCORPORATED LATER INTO TIGHT JUNCTIONS 
 
National Institutes of Health

Papers overview

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2010
2010
Genetic analysis of the regulation of type IV pilus function by the Chp chemosensory system of Pseudomonas aeruginosa.
The virulence of the opportunistic pathogen Pseudomonas aeruginosa involves the coordinate expression of many virulence factors… (More)
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Highly Cited
2006
Highly Cited
2006
Virus-Induced Abl and Fyn Kinase Signals Permit Coxsackievirus Entry through Epithelial Tight Junctions
Group B coxsackieviruses (CVBs) must cross the epithelium as they initiate infection, but the mechanism by which this occurs… (More)
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Highly Cited
2006
Highly Cited
2006
A systematic genetic analysis in Neisseria meningitidis defines the Pil proteins required for assembly, functionality, stabilization and export of type IV pili.
Although type IV pili (Tfp) are among the commonest virulence factors in bacteria, their biogenesis by complex machineries of 12… (More)
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Highly Cited
2006
Highly Cited
2006
Increased blood–brain barrier permeability and altered tight junctions in experimental diabetes in the rat: contribution of hyperglycaemia and matrix metalloproteinases
Although diabetes mellitus is associated with peripheral microvascular complications and increased risk of neurological events… (More)
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Highly Cited
2002
Highly Cited
2002
Single pilus motor forces exceed 100 pN.
Force production by type IV pilus retraction is critical for infectivity of Neisseria gonorrhoeae and DNA transfer. We… (More)
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Highly Cited
2002
Highly Cited
2002
Competence for natural transformation in Neisseria gonorrhoeae: components of DNA binding and uptake linked to type IV pilus expression.
The mechanisms by which DNA is taken up into the bacterial cell during natural genetic transformation are poorly understood… (More)
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Highly Cited
2000
Highly Cited
2000
Components and dynamics of fiber formation define a ubiquitous biogenesis pathway for bacterial pili.
Type IV pili (Tfp) are a unique class of multifunctional surface organelles in Gram-negative bacteria, which play important roles… (More)
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Highly Cited
2000
Highly Cited
2000
Type IV pilus biogenesis and motility in the cyanobacterium Synechocystis sp. PCC6803.
We have recently shown that phototactic movement in the unicellular cyanobacterium Synechocystis sp. PCC6803 requires type IV… (More)
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Highly Cited
1999
Highly Cited
1999
Pseudomonas aeruginosa gene products PilT and PilU are required for cytotoxicity in vitro and virulence in a mouse model of acute pneumonia.
Type IV pili of the opportunistic pathogen Pseudomonas aeruginosa mediate twitching motility and act as receptors for… (More)
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Highly Cited
1998
Highly Cited
1998
PilT mutations lead to simultaneous defects in competence for natural transformation and twitching motility in piliated Neisseria gonorrhoeae.
Neisseria gonorrhoeae, the Gram-negative aetiological agent of gonorrhoeae, is one of many mucosal pathogens of man that… (More)
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