TITF1 protein, human

Known as: Homeobox protein NK-2 homolog A, Thyroid Transcription Factor, Homeobox protein Nkx-2.1 
Thyroid transcription factor 1 (371 aa, ~39 kDa) is encoded by the human NKX2-1 gene. This protein is involved in transcriptional regulation.
National Institutes of Health

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Highly Cited
2012
Highly Cited
2012
We and others previously identified NKX2-1, also known as TITF1 and TTF-1, as a lineage-survival oncogene in lung adenocarcinomas… (More)
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Highly Cited
2012
Highly Cited
2012
The primary function of the thyroid gland is to metabolize iodide by synthesizing thyroid hormones, which are critical regulators… (More)
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2010
2010
CONTEXT Gene mutations of transcription factors that are predominantly expressed in the thyroid gland cause congenital… (More)
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Highly Cited
2008
Highly Cited
2008
Lung cancer is a leading cause of cancer death, where the amplification of oncogenes contributes to tumorigenesis. Genomic… (More)
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2004
2004
OBJECTIVE To study the NKX2-1 gene in two half-siblings with elevated thyroid-stimulating hormone (TSH) on state screen… (More)
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Highly Cited
2002
Highly Cited
2002
The occurrence of neurological symptoms and developmental delay in patients affected by congenital hypothyroidism (CH) has been… (More)
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Highly Cited
2001
Highly Cited
2001
Transgenic mice in which fibroblast growth factor (FGF)-10 was expressed in the lungs of fetal and postnatal mice were generated… (More)
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2001
2001
We studied 14 mucinous and 26 nonmucinous bronchioloalveolar adenocarcinomas (BACs) with thyroid transcription factor (TTF… (More)
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Review
2001
Review
2001
Insulin regulates the expression of more than 150 genes, indicating that this is a major action of this hormone. At least eight… (More)
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1997
1997
The hormonal regulation of both thyroglobulin and thyroperoxidase promoter activity in FRTL-5 thyroid cells takes place, at least… (More)
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