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TIMP4 protein, human

Known as: tissue inhibitor of metalloproteinase 4 protein, human, TIMP-4, Tissue Inhibitor of Metalloproteinases 4 
Metalloproteinase inhibitor 4 (224 aa, ~26 kDa) is encoded by the human TIMP4 gene. This protein plays a role in the inhibition of matrix… 
National Institutes of Health

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Related topics

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Extracellular SpaceGenes, RegulatorInhibition of Matrix Metalloproteinases PathwayProtein Degradation Inhibition

Broader (1)

tissue inhibitor of metalloproteinase 4

Papers overview

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2016
2016
LBPS 02-52 EFFECT OF EMPAGLIFLOZIN ON HEART FAILURE OUTCOMES IN SUBGROUPS BY AGE: RESULTS FROM EMPA-REG OUTCOME
Objective: In the EMPA-REG OUTCOME trial, empagliflozin added to standard of care significantly reduced 3-point major adverse… 
2016
2016
Abstract P2-05-25: TIMP-4 expression correlates with disease progression among HER2-positive breast cancers
Breast cancer with HER2 gene amplification accounts for 20-25% of invasive breast cancer. HER2 activates the PI3K/Akt and MAPK… 
2016
2016
Metalloproteinases and Their issue Inhibitors in Pressure-Overloaded uman Myocardium During Heart Failure Progression
OBJECTIVES We studied the role of matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) in fibrosis formation in… 
2015
2015
Исследование факторов регуляции экстраклеточного матрикса и биомеханических свойств корнеосклеральной оболочки при физиологическом старении и первичной открытоугольной глаукоме
PURPOSE: Comparative analysis of the biomechanical parameters of the fibrous tunic of the eyeball and extracellular matrix (ECM… 
2015
2015
The Distribution of Matrix Metalloproteinase - 2, Tissue Inhibitor of Metalloproteinase - 2 and Tissue Inhibitor of Metalloproteinase - 4 in Psoriatic Skin
Aims: To evaluate the appearance and distribution of matrix metalloproteinase-2 (MMP-2), tissue inhibitor of metalloproteinase-2… 
2015
2015
[Evaluation of tissue metaloproteinases inhibitors TIMP-2 and TIMP-4 in III-rd trimester of pregnancy].
INTRODUCTION To achieve physiological pregnancy development proper implantation and placental development is needed to establish… 
2010
2010
GENDER RELATED DIFFERENCES IN HUMOR MATRIX METALLOPROTEINASES MMP-2 ACTIVITY AND TISSUE INHIBITOR OF MATRIX METALLOPROTEINASES IN PATIENTS WITH PSEUDOEXFOLIATION SYNDROME / GLAUCOMA
Pseudoexfoliation syndrome (PEX Sy) is a common age–related disorder of the extracellular matrix that is frequently associated… 
2008
2008
[The evidence of matrix metalloproteinases and its tissue inhibitors in children's affected gingiva].
Matrix metalloproteinases (MMP) and its tissue inhibitors (TIMP) were studied in 14 affected and 11 "control" samples from… 
2004
2004
Endometrial TIMP-4 mRNA is high at midcycle and in hyperplasia, but down-regulated in malignant tumours. Coordinated expression with MMP-26.
We have previously reported that endometrial expression of matrix metalloproteinase (MMP)-26 mRNA comes to a maximum in the early… 
2001
2001
Inhibition of ADAMTS 4 ( aggrecanase-1 ) by tissue inhibitors of metalloproteinases ( TIMP-1 , 2 , 3 and 4 )
ADAMTS4 (aggrecanase-1) is considered to play a key role in the degradation of aggrecan in arthritides. The inhibitory activity…