TIMD4 gene

Known as: TIM4, TIMD4, T-cell immunoglobulin and mucin domain containing 4 
 
National Institutes of Health

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Broader (1)

Genes

Papers overview

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Review
2017
Review
2017
Targeting hepatic macrophages to treat liver diseases.
Our view on liver macrophages in the context of health and disease has been reformed by the recognition of a remarkable… (More)
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2016
2016
A novel affinity-based method for the isolation of highly purified extracellular vesicles
Extracellular vesicles (EVs) such as exosomes and microvesicles serve as messengers of intercellular network, allowing exchange… (More)
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2014
2014
The phosphatidylserine receptor TIM4 utilizes integrins as coreceptors to effect phagocytosis
T-cell immunoglobulin mucin protein 4 (TIM4), a phosphatidylserine (PtdSer)-binding receptor, mediates the phagocytosis of… (More)
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2014
2014
Molecular mechanism for differential recognition of membrane phosphatidylserine by the immune regulatory receptor Tim4.
Recognition of phosphatidylserine (PS) lipids exposed on the extracellular leaflet of plasma membranes is implicated in both… (More)
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2012
2012
Synergistic effect of Tim4 and MFG-E8 null mutations on the development of autoimmunity.
Phagocytes, including macrophages, recognize phosphatidylserine exposed on apoptotic cells as an "eat me" signal. Milk Fat… (More)
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2010
2010
TIM1 is an endogenous ligand for LMIR5/CD300b: LMIR5 deficiency ameliorates mouse kidney ischemia/reperfusion injury
Leukocyte mono-immunoglobulin (Ig)-like receptor 5 (LMIR5)/CD300b is a DAP12-coupled activating receptor predominantly expressed… (More)
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2008
2008
Disruption of T-cell immunoglobulin and mucin domain molecule (TIM)-1/TIM4 interaction as a therapeutic strategy in a dendritic cell-induced peanut allergy model.
BACKGROUND Recent reports indicate that dendritic cell (DC)-derived T-cell immunoglobulin and mucin domain molecule (TIM)-4 plays… (More)
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Highly Cited
2007
Highly Cited
2007
Identification of Tim4 as a phosphatidylserine receptor
In programmed cell death, a large number of cells undergo apoptosis, and are engulfed by macrophages to avoid the release of… (More)
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2007
2007
Staphylococcal enterotoxin B increases TIM4 expression in human dendritic cells that drives naïve CD4 T cells to differentiate into Th2 cells.
Aberrant T helper (Th)2 polarization plays a critical role in the pathogenesis of allergic disorders; the etiology remains… (More)
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1972
1972
Altered regulation of the transport of RNA from nucleus to cytoplasm in rat hepatoma cells.
One characteristic of tumor cells which has stimulated much discussion and study is the presence of proteins not found in the… (More)
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