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TIMD4 gene

Known as: TIM4, TIMD4, T-cell immunoglobulin and mucin domain containing 4 
 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Genes

Papers overview

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Highly Cited
2018
Highly Cited
2018
Self-renewing resident cardiac macrophages limit adverse remodeling following myocardial infarction
Macrophages promote both injury and repair after myocardial infarction, but discriminating functions within mixed populations… Expand
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Review
2017
Review
2017
Targeting hepatic macrophages to treat liver diseases.
  • F. Tacke
  • Journal of hepatology
  • 2017
    • Corpus ID: 3985605
Our view on liver macrophages in the context of health and disease has been reformed by the recognition of a remarkable… Expand
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Highly Cited
2016
Highly Cited
2016
A novel affinity-based method for the isolation of highly purified extracellular vesicles
Extracellular vesicles (EVs) such as exosomes and microvesicles serve as messengers of intercellular network, allowing exchange… Expand
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Highly Cited
2014
Highly Cited
2014
The phosphatidylserine receptor TIM4 utilizes integrins as coreceptors to effect phagocytosis
TIM4 is a receptor for phosphatidylserine that mediates engulfment of apoptotic cells. Remarkably, it does not require its… Expand
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2014
2014
Molecular mechanism for differential recognition of membrane phosphatidylserine by the immune regulatory receptor Tim4
Significance Structural immunology employs static, atomic-level representations to uncover the molecular mechanisms by which… Expand
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Highly Cited
2010
Highly Cited
2010
TIM1 is an endogenous ligand for LMIR5/CD300b: LMIR5 deficiency ameliorates mouse kidney ischemia/reperfusion injury
Leukocyte mono-immunoglobulin (Ig)–like receptor 5 (LMIR5)/CD300b is a DAP12-coupled activating receptor predominantly expressed… Expand
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Highly Cited
2008
Highly Cited
2008
Disruption of T-cell immunoglobulin and mucin domain molecule (TIM)-1/TIM4 interaction as a therapeutic strategy in a dendritic cell-induced peanut allergy model.
BACKGROUND Recent reports indicate that dendritic cell (DC)-derived T-cell immunoglobulin and mucin domain molecule (TIM)-4 plays… Expand
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Highly Cited
2007
Highly Cited
2007
Identification of Tim4 as a phosphatidylserine receptor
In programmed cell death, a large number of cells undergo apoptosis, and are engulfed by macrophages to avoid the release of… Expand
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Highly Cited
2007
Highly Cited
2007
Staphylococcal enterotoxin B increases TIM4 expression in human dendritic cells that drives naïve CD4 T cells to differentiate into Th2 cells.
Aberrant T helper (Th)2 polarization plays a critical role in the pathogenesis of allergic disorders; the etiology remains… Expand
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Highly Cited
1972
Highly Cited
1972
Altered regulation of the transport of RNA from nucleus to cytoplasm in rat hepatoma cells.
Summary RNA base sequences that are restricted to the nucleus in normal rat liver are found in the cytoplasm in azo dye-induced… Expand
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