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TIAM1 Protein
Known as:
T-Lymphoma Invasion and Metastasis Inducing Protein 1
, TIAM1
TIAM1 appears to function in cellular signaling by modulating activation the GDP-GTP exchange activity of RHO-like GTPases that regulate cytoskeletal…
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National Institutes of Health
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Related topics
Related topics
5 relations
Brain
Signal Transduction
Signaling Pathway Gene
TIAM1 gene
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
miRNA-218 inhibits osteosarcoma cell migration and invasion by down-regulating of TIAM1, MMP2 and MMP9.
Jie Jin
,
L. Cai
,
Zhi-ming Liu
,
Xuechun Zhou
Asian Pacific Journal of Cancer Prevention
2013
Corpus ID: 17470742
Deregulated miRNAs participate in osteosarcoma genesis. In this study, the expression of miRNA-218 in human osteosarcomas…
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Highly Cited
2010
Highly Cited
2010
Syndecan-2 regulates cell migration in colon cancer cells through Tiam1-mediated Rac activation.
Youngsil Choi
,
Hyun-joong Kim
,
+4 authors
E. Oh
Biochemical and Biophysical Research…
2010
Corpus ID: 45178260
2009
2009
Progression of breast tumors is accompanied by a decrease in expression of the Rho guanine exchange factor Tiam1.
A. Stebel
,
C. Brachetti
,
M. Kunkel
,
M. Schmidt
,
G. Fritz
Oncology Report
2009
Corpus ID: 42728236
In this study, we investigated the expression level of Ras-homologous (Rho) GTPases and the Rho guanine exchange factor (GEF) T…
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2008
2008
Integrin alpha 6 beta 4 promotes migration, invasion through Tiam1 upregulation, and subsequent Rac activation.
Z. Cruz-Monserrate
,
K. O’Connor
Neoplasia
2008
Corpus ID: 19908832
The lethality of pancreatic adenocarcinoma stems from an elevated incidence of tumor cell invasion and metastasis that are…
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Review
2006
Review
2006
Wnt signalling in the mouse intestine
A. Clarke
Oncogene
2006
Corpus ID: 21425797
The ApcMin/+ mouse has emerged as a powerful model of human intestinal tumour predisposition. As such, it has provided a platform…
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2004
2004
The in vivo roles of STEF/Tiam1, Rac1 and JNK in cortical neuronal migration
川内 健史
2004
Corpus ID: 88307733
2002
2002
Tumor metastasis suppressor nm23H1 regulates Rac1 GTPase by interaction with Tiam1
大月 寛郎
2002
Corpus ID: 86883183
Highly Cited
2000
Highly Cited
2000
Regulation of Tiam1 Nucleotide Exchange Activity by Pleckstrin Domain Binding Ligands*
A. Crompton
,
L. Foley
,
+5 authors
G. Bollag
Journal of Biological Chemistry
2000
Corpus ID: 25881460
Rho family GTPases play roles in cytoskeletal organization and cellular transformation. Tiam1 is a member of the Dbl family of…
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Highly Cited
1999
Highly Cited
1999
Tiam1 is involved in the regulation of bufalin-induced apoptosis in human leukemia cells
N. Kawazoe
,
M. Watabe
,
Y. Masuda
,
S. Nakajo
,
K. Nakaya
Oncogene
1999
Corpus ID: 20034380
Bufalin, a component of the Chinese medicine chan'su, induces apoptosis in various lines of human tumor cells, such as leukemia…
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Highly Cited
1996
Highly Cited
1996
Isolation of a novel oncogene, NET1, from neuroepithelioma cells by expression cDNA cloning.
A. Chan
,
S. Takai
,
K. Yamada
,
T. Miki
Oncogene
1996
Corpus ID: 45937459
We generated a cDNA expression library from a human neuroepithelioma cell line for detection of novel oncogenes by focus…
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