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THBD protein, human

Known as: CD141 Antigen, thrombomodulin, human, TM 
Thrombomodulin (575 aa, ~60 kDa) is encoded by the human THBD gene. This protein plays a role in thrombin binding, fibrinolysis and coagulation.
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
In recent years, human dendritic cells (DCs) could be subdivided into CD304+ plasmacytoid DCs (pDCs) and conventional DCs (cDCs… Expand
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Highly Cited
2010
Highly Cited
2010
In humans and mice, CD8α+ conventional dendritic cells are the primary source of interferon-λ released in response to the… Expand
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Highly Cited
2007
Highly Cited
2007
Human blood contains 2 populations of dendritic cells (DCs): plasmacytoid and myeloid (mDC). mDCs are subdivided into 3 subsets… Expand
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Highly Cited
2005
Highly Cited
2005
Thrombomodulin (TM) is an endothelial anticoagulant cofactor that promotes thrombin-mediated formation of activated protein C… Expand
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Highly Cited
2002
Highly Cited
2002
Dendritic cells (DCs) are key antigen-presenting cells for stimulating immune responses and they are now being investigated in… Expand
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Highly Cited
2000
Highly Cited
2000
We have generated a panel of mAbs that identify three presumably novel human dendritic cell Ags: BDCA-2, BDCA-3, and BDCA-4. In… Expand
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Review
1996
Review
1996
Vascular endothelium is strategically located at the interface between tissue and blood. It is pivotal for protecting against… Expand
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Review
1995
Review
1995
  • Charles T. Esmon
  • FASEB journal : official publication of the…
  • 1995
  • Corpus ID: 19565674
The protein C anticoagulant system generates an "on demand" physiologic anticoagulant response. The pathway is initiated when… Expand
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Highly Cited
1987
Highly Cited
1987
We have deduced the entire 575-amino acid sequence of the human thrombomodulin precursor from cDNA clones. The precursor starts… Expand
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Highly Cited
1985
Highly Cited
1985
Thrombomodulin is an endothelial cell membrane protein that is a cofactor required for the rapid activation of plasma protein C… Expand
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