TGFBR2 protein, human

Known as: TGFR-2, TGF B Receptor, Transforming Growth Factor Beta Receptor 
TGF-beta receptor type-2 (567 aa, ~65 kDa) is encoded by the human TGFBR2 gene. This protein plays a role in both serine/threonine phosphorylation… (More)
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
TGF-β is essential for vascular development; however, excess TGF-β signaling promotes thoracic aortic aneurysm and dissection in… (More)
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Highly Cited
2008
Highly Cited
2008
Aberrant TGFbeta signaling is common in human cancers and contributes to tumor metastasis. Here, we demonstrate that Gr-1+CD11b… (More)
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Highly Cited
2006
Highly Cited
2006
Pancreatic ductal adenocarcinoma (PDAC) is an almost uniformly lethal disease in humans. Transforming growth factor-beta (TGF… (More)
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Highly Cited
2006
Highly Cited
2006
Palatal fusion is a complex, multi-step developmental process; the consequence of failure in this process is cleft palate, one of… (More)
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Highly Cited
2003
Highly Cited
2003
Cleft palate and skull malformations represent some of the most frequent congenital birth defects in the human population… (More)
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Highly Cited
2002
Highly Cited
2002
In this study we have examined the interaction between CD44 (a hyaluronan (HA) receptor) and the transforming growth factor beta… (More)
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Highly Cited
2001
Highly Cited
2001
Binding of erythropoietin (Epo) to the Epo receptor (EpoR) is crucial for production of mature red cells. Although it is well… (More)
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Highly Cited
1999
Highly Cited
1999
Activation of the type I TGFbeta receptor (TbetaR-I) requires phosphorylation of a regulatory segment known as the GS region… (More)
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Highly Cited
1997
Highly Cited
1997
Insulin-like growth factor-binding protein 3 (IGFBP-3) has been shown to inhibit cell growth by IGF-dependent and -independent… (More)
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Highly Cited
1996
Highly Cited
1996
TGF-beta signaling is mediated through two types of serine/threonin kinase-containing receptors, type I (TGF-betaRI) and type II… (More)
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