TGFBR1 protein, human

Known as: ALK5 protein, human, TGF-Beta Type I Receptor, TGFR-1 
TGF-beta receptor type-1 (503 aa, ~56 kDa) is encoded by the human TGFBR1 gene. This protein plays a role in both TGF-beta-dependent signaling and… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
nature medicine volume 18 | number 3 | mArCH 2012 349 of one (vandetanib) for the treatment of adults with metastatic medullary… (More)
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Highly Cited
2010
Highly Cited
2010
Mesenchymal stem cells (MSCs) are bone marrow stromal cells that can differentiate into multiple lineages. We previously… (More)
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Highly Cited
2008
Highly Cited
2008
The relationship between bile duct damage and portal fibrosis in chronic liver diseases remains unclear. This study was designed… (More)
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Highly Cited
2008
Highly Cited
2008
It is known that the activation of hedgehog (Hh) signaling is involved in the progression and invasion of various tumors… (More)
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Review
2005
Review
2005
Genetic studies in mice and humans have revealed the pivotal role of transforming growth factor-beta (TGF-beta) signaling during… (More)
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Highly Cited
2004
Highly Cited
2004
We have examined overexpression of the human epidermal growth factor receptor 2 (HER2) to determine if it modifies the anti… (More)
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Highly Cited
2004
Highly Cited
2004
Hereditary haemorrhagic telangiectasia (HHT) is an autosomal dominant disorder in humans that is characterised by multisystemic… (More)
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Highly Cited
2002
Highly Cited
2002
The generation of mice lacking specific components of the transforming growth factor-beta (TGF-beta) signal tranduction pathway… (More)
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Highly Cited
2002
Highly Cited
2002
Small molecule inhibitors have proven extremely useful for investigating signal transduction pathways and have the potential for… (More)
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Highly Cited
2000
Highly Cited
2000
The activin receptor-like kinase 1 (ALK1) is a type I receptor for transforming growth factor-beta (TGF-beta) family proteins… (More)
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