TFEB protein, human

Known as: Transcription Factor EB, bHLHe35, transcription factor EB, human 
Transcription factor EB (476 aa, ~53 kDa) is encoded by the human TFEB gene. This protein plays a role in transcriptional regulation.
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Autophagy is a conserved pathway that delivers cytoplasmic contents to the lysosome for degradation. Here we consider its roles… (More)
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Highly Cited
2015
Highly Cited
2015
The view of the lysosome as the terminal end of cellular catabolic pathways has been challenged by recent studies showing a… (More)
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Highly Cited
2013
Highly Cited
2013
The aggregation of α-synuclein plays a major role in Parkinson disease (PD) pathogenesis. Recent evidence suggests that defects… (More)
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Highly Cited
2013
Highly Cited
2013
The mTORC1 complex supports cell growth and proliferation in response to energy levels, growth factors, and nutrients. The Rag… (More)
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Highly Cited
2012
Highly Cited
2012
The lysosome plays a key role in cellular homeostasis by controlling both cellular clearance and energy production to respond to… (More)
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Highly Cited
2012
Highly Cited
2012
The mammalian target of rapamycin (MTOR) protein kinase complex is a key component of a pathway that regulates cell growth and… (More)
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Highly Cited
2012
Highly Cited
2012
Lysosomes are the major cellular site for clearance of defective organelles and digestion of internalized material. Demand on… (More)
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Highly Cited
2011
Highly Cited
2011
Autophagy is a cellular catabolic process that relies on the cooperation of autophagosomes and lysosomes. During starvation, the… (More)
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Highly Cited
2011
Highly Cited
2011
Mammalian target of rapamycin (mTOR) complex 1 (mTORC1) is an important, highly conserved, regulator of cell growth. Ancient… (More)
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Highly Cited
2003
Highly Cited
2003
MITF, TFE3, TFEB, and TFEC comprise a transcription factor family (MiT) that regulates key developmental pathways in several cell… (More)
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