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TFCP2L1 gene

Known as: LBP9, CP2-RELATED TRANSCRIPTIONAL REPRESSOR 1, LBP-9 
 
National Institutes of Health

Papers overview

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2018
2018
Tfcp2l1 safeguards the maintenance of human embryonic stem cell self-renewal.
Tfcp2l1 is a transcription factor critical for mouse embryonic stem cell (mESC) maintenance. However, its role in human ESCs… Expand
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2017
2017
Transcription factor TFCP2L1 patterns cells in the mouse kidney collecting ducts
Although most nephron segments contain one type of epithelial cell, the collecting ducts consists of at least two: intercalated… Expand
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2017
2017
TFCP2L1 represses multiple lineage commitment of mouse embryonic stem cells through MTA1 and LEF1.
TFCP2L1 is a transcription factor that is crucial for self-renewal of mouse embryonic stem cells (mESCs). How TFCP2L1 maintains… Expand
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2015
2015
Klf2 and Tfcp2l1, Two Wnt/β-Catenin Targets, Act Synergistically to Induce and Maintain Naive Pluripotency
Summary Activation of Wnt/β-catenin signaling can induce both self-renewal and differentiation in naive pluripotent embryonic… Expand
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Highly Cited
2014
Highly Cited
2014
Primate-specific endogenous retrovirus-driven transcription defines naive-like stem cells
Naive embryonic stem cells hold great promise for research and therapeutics as they have broad and robust developmental potential… Expand
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Highly Cited
2013
Highly Cited
2013
Embryonic stem cell self-renewal pathways converge on the transcription factor Tfcp2l1.
Mouse embryonic stem cell (mESC) self-renewal can be maintained by activation of the leukaemia inhibitory factor (LIF)/signal… Expand
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Highly Cited
2013
Highly Cited
2013
Identification of the missing pluripotency mediator downstream of leukaemia inhibitory factor
Self-renewal of pluripotent mouse embryonic stem (ES) cells is sustained by the cytokine leukaemia inhibitory factor (LIF) acting… Expand
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2005
2005
LBP proteins modulate SF1-independent expression of P450scc in human placental JEG-3 cells.
The cholesterol side-chain cleavage enzyme, P450scc, initiates biosynthesis of all steroid hormones. Adrenal and gonadal P450scc… Expand
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Highly Cited
2002
Highly Cited
2002
A highly conserved novel family of mammalian developmental transcription factors related to Drosophila grainyhead
The Drosophila transcription factor Grainyhead regulates several key developmental processes. Three mammalian genes, CP2, LBP-1a… Expand
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2000
2000
Cloning of factors related to HIV-inducible LBP proteins that regulate steroidogenic factor-1-independent human placental transcription of the cholesterol side-chain cleavage enzyme, P450scc.
The cholesterol side-chain cleavage enzyme, cytochrome P450scc, initiates the biosynthesis of all steroid hormones. Adrenal and… Expand
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