TET2 gene

Known as: TET2, FLJ20032, TET ONCOGENE FAMILY, MEMBER 2 
This gene is involved in oxidation.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Ten eleven translocation (TET) enzymes, including TET1, TET2 and TET3, convert 5-methylcytosine to 5-hydroxymethylcytosine and… (More)
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Highly Cited
2013
Highly Cited
2013
Tet enzymes (Tet1/2/3) convert 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC) in various embryonic and adult tissues… (More)
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Highly Cited
2011
Highly Cited
2011
TET2 is mutated/deleted with high frequencies in multiple forms of myeloid malignancies including MDS, CMML, MPN, and AML… (More)
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Highly Cited
2011
Highly Cited
2011
The Ten-Eleven-Translocation 2 (TET2) gene encodes a member of TET family enzymes that alters the epigenetic status of DNA by… (More)
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Highly Cited
2011
Highly Cited
2011
PURPOSE To determine the frequency of TET2 mutations, their associations with clinical and molecular characteristics and outcome… (More)
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Highly Cited
2010
Highly Cited
2010
Cancer-associated IDH mutations are characterized by neomorphic enzyme activity and resultant 2-hydroxyglutarate (2HG) production… (More)
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Highly Cited
2010
Highly Cited
2010
TET2 is a close relative of TET1, an enzyme that converts 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC) in DNA. The… (More)
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Highly Cited
2009
Highly Cited
2009
To the Editor: The finding of Delhommeau and colleagues that TET2 mutations occur in myeloid cancers (May 28 issue)1 has been… (More)
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Highly Cited
2009
Highly Cited
2009
Myelodysplastic syndromes (MDS) represent a heterogeneous group of neoplastic hematopoietic disorders. Several recurrent… (More)
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Highly Cited
2009
Highly Cited
2009
Chromosomal abnormalities are frequent in myeloid malignancies, but in most cases of myelodysplasia (MDS) and myeloproliferative… (More)
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