TEL-AML1 fusion protein

Known as: ETV6-RUNX1 Fusion Protein, MDS-1-EVI1 fusion protein, TEL/AML1 Fusion Protein 
A fusion protein encoded by the ETV6/RUNX1 fusion gene. This protein is comprised of the N-terminal DNA binding helix-loop-helix domain of the… (More)
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Understanding cancer pathogenesis requires knowledge of not only the specific contributory genetic mutations but also the… (More)
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2007
2007
The t(12;21)(p13;q22) translocation generates the TEL-AML1 (TEL, translocation-Ets-leukemia; AML1, acute myeloid leukemia-1… (More)
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Highly Cited
2003
Highly Cited
2003
Contemporary treatment of pediatric acute lymphoblastic leukemia (ALL) requires the assignment of patients to specific risk… (More)
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Highly Cited
2002
Highly Cited
2002
Treatment of pediatric acute lymphoblastic leukemia (ALL) is based on the concept of tailoring the intensity of therapy to a… (More)
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Highly Cited
2002
Highly Cited
2002
TEL-AML1 is expressed from the t(12;21) chromosomal translocation inB-precursor acute lymphocytic leukemia (ALL). Creation of the… (More)
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Highly Cited
1999
Highly Cited
1999
We report a pair of identical twins with concordant acute lymphoblastic leukemia (ALL). Unusually, their diagnoses were spaced 9… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND There is little current insight into the natural history of childhood leukaemia or the timing of relevant mutational… (More)
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1999
1999
TEL-AML1 gene fusion derived by chromosomal translocation is a common acquired genetic lesion in pediatric cancer that is present… (More)
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Highly Cited
1996
Highly Cited
1996
A recurrent t(12;21)(p13;q22) has recently been described in human acute lymphoblastic leukemias (ALLs). This translocation fuses… (More)
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Highly Cited
1996
Highly Cited
1996
Primary congenital glaucoma (gene symbol: GLC3) is an ocular disorder that occurs for 0.01-0.04% of blind people. In the majority… (More)
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