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TEK gene

Known as: TIE2, TEK TYROSINE KINASE, ENDOTHELIAL, CD202b 
This gene plays a role in vascular development and angiogenesis.
National Institutes of Health

Related topics

Related topics

12 relations
Angiogenic ProcessAngiopoietin-1 Receptor, HumanCell Differentiation processCell Proliferation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Searching for molecular targets in sarcoma.
Highly Cited
2007
Highly Cited
2007
Evolution of a highly selective and potent 2-(pyridin-2-yl)-1,3,5-triazine Tie-2 kinase inhibitor.
Inhibition of angiogenesis is a promising and clinically validated approach for limiting tumor growth and survival. The receptor… 
Highly Cited
2005
Highly Cited
2005
The potential of angiogenesis soluble markers in chronic hepatitis C
Angiogenesis, the formation of new vessels, has been reported to play a significant pathogenic role in liver damage–associated… 
Highly Cited
2004
Highly Cited
2004
Targeting the Tie2/Tek receptor in astrocytomas.
Highly Cited
2004
Highly Cited
2004
Adaptor ShcA Protein Binds Tyrosine Kinase Tie2 Receptor and Regulates Migration and Sprouting but Not Survival of Endothelial Cells*
Angiopoietin-1 can promote migration, sprouting, and survival of endothelial cells through activation of different signaling… 
Highly Cited
2004
Highly Cited
2004
Hepatic expression of ANG2 RNA in metastatic colorectal cancer
We examined the RNA content of the gene encoding angiopoietin (Ang)‐2, a modifier of angiogenesis, in hepatic metastases of… 
Highly Cited
2003
Highly Cited
2003
Shear stress activates Tie2 receptor tyrosine kinase in human endothelial cells.
Highly Cited
2003
Highly Cited
2003
DITPA stimulates bFGF, VEGF, angiopoietin, and Tie-2 and facilitates coronary arteriolar growth.
Previous studies from our laboratory and those of others have shown thyroxine to be a stimulator of coronary microvascular growth… 
Review
2002
Review
2002
Getting Tie(2)d up in angiogenesis.
Angiogenesis, the growth of new vessels from pre-existing blood vessels, requires complex signaling pathways and a high degree of… 
Highly Cited
2001
Highly Cited
2001
Significant correlation between interleukin 10 expression and vascularization through angiopoietin/TIE2 networks in non-small cell lung cancer.
The expression of interleukin 10 (IL-10) is correlated with clinical prognosis in non-small cell lung cancer [NSCLC (H. Hatanaka… 
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