TEK gene

Known as: TIE2, TEK TYROSINE KINASE, ENDOTHELIAL, CD202b 
This gene plays a role in vascular development and angiogenesis.
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Angiopoietin 2 (Ang2) was originally shown to be a competitive antagonist for Ang1 of the receptor tyrosine kinase Tie2 in… (More)
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Highly Cited
2007
Highly Cited
2007
Dicer is a key enzyme involved in the maturation of microRNAS (miRNAs). miRNAs have been shown to be regulators of gene… (More)
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Highly Cited
2004
Highly Cited
2004
The quiescent state is thought to be an indispensable property for the maintenance of hematopoietic stem cells (HSCs… (More)
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Highly Cited
2001
Highly Cited
2001
An abnormal pulmonary vasculature may be an important component of bronchopulmonary dysplasia (BPD). We examined human infant… (More)
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Highly Cited
1999
Highly Cited
1999
The Tek/Tie2 receptor tyrosine kinase plays a pivotal role in vascular and hematopoietic development. To study the signal… (More)
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Highly Cited
1997
Highly Cited
1997
Angiogenesis is thought to depend on a precise balance of positive and negative regulation. Angiopoietin-1 (Ang1) is an… (More)
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Highly Cited
1996
Highly Cited
1996
Vascular endothelial growth factor (VEGF), which acts via members of a family of endothelial-specific receptor tyrosine kinases… (More)
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Highly Cited
1996
Highly Cited
1996
TIE2 is a receptor-like tyrosine kinase expressed almost exclusively in endothelial cells and early hemopoietic cells and… (More)
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Highly Cited
1995
Highly Cited
1995
TIE-1 and Tie-2 define a new class of receptor tyrosine kinases that are specifically expressed in developing vascular… (More)
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Highly Cited
1993
Highly Cited
1993
To identify receptor tyrosine kinases (RTKs) critical to early hematopoiesis, we performed polymerase chain reaction-based… (More)
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