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TBX5 gene

Known as: T-BOX 5, T-Box 5 Gene, TBX5 
This gene is involved in transcriptional regulation and mesoderm differentiation.
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
The cardiac conduction system is an anatomically discrete segment of specialized myocardium that initiates and propagates… Expand
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Highly Cited
2003
Highly Cited
2003
Congenital heart defects (CHDs) are the most common developmental anomaly and are the leading non-infectious cause of mortality… Expand
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Highly Cited
2003
Highly Cited
2003
Transcriptional cascades responsible for initiating the formation of vertebrate embryonic structures such as limbs are not well… Expand
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Highly Cited
2002
Highly Cited
2002
Holt-Oram syndrome is one of the autosomal dominant human "heart-hand" disorders, with a combination of upper limb malformations… Expand
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Highly Cited
2001
Highly Cited
2001
The cardiac homeobox protein Nkx2-5 is essential in cardiac development, and mutations in Csx (which encodes Nkx2-5) cause… Expand
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Highly Cited
1999
Highly Cited
1999
To better understand the role of TBX5, a T-box containing transcription factor in forelimb and heart development, we have studied… Expand
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Highly Cited
1999
Highly Cited
1999
During embryonic development, initially similar fields can develop into distinct structures, such as the vertebrate fore- and… Expand
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Highly Cited
1997
Highly Cited
1997
Holt-Oram syndrome is a developmental disorder affecting the heart and upper limb, the gene for which was mapped to chromosome 12… Expand
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Highly Cited
1997
Highly Cited
1997
Holt-Oram syndrome is characterized by upper limb malformations and cardiac septation defects. Here, we demonstrate that… Expand
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Highly Cited
1997
Highly Cited
1997
Holt-Oram syndrome is characterized by upper limb malformations and cardiac septation defects. Here, we demonstrate that… Expand
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