TBX19 gene

1) those that are turned on and off byinput from the user; and 2) single-use pumps that are turnedon autonomously by exposure to… Expand

Despite the existence of interspecies phenotypic variability, animal models have yielded valuable insights into human pituitary… Expand

The signaling molecules bone morphogenic protein (BMP) 4 and 2 have been implicated in early organogenesis and cell… Expand

NeuroD1(BETA2) and Tpit are cell-specific activators of pituitary proopiomelanocortin (POMC) gene transcription. Expression of… Expand

OBJECTIVE Congenital isolated ACTH deficiency (IAD) is a rare inherited disorder that is clinically and genetically heterogeneous… Expand

The T-box transcription factor Tpit was identified as a cell-specific factor for expression of the pituitary proopiomelanocortin… Expand

Tpit is a highly cell-restricted transcription factor that is required for expression of the pro-opiomelanocortin (POMC) gene and… Expand

Since the identification of the pituitary-restricted transcription factor Tpit, a novel T-box factor that is only present in… Expand

Pituitary cell types arise in a temporally and spatially specific fashion, in response to combinatorial actions of transcription… Expand

Brachyury(T) is a mouse mutation, first described over 70 years ago, that causes defects in mesoderm formation. Recently several… Expand