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TAK 285
Known as:
EGFR/HER2 Kinase Inhibitor TAK-285
, TAK-285
, TAK285
An orally bioavailable, small molecule and dual kinase inhibitor of human epidermal growth factor receptors 1 (EGFR/ErbB1) and 2 (HER2/ErbB2), with…
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National Institutes of Health
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Related topics
Related topics
2 relations
NCIt Antineoplastic Agent Terminology
Receptor Tyrosine Kinase Inhibition
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Template-Based de Novo Design for Type II Kinase Inhibitors and Its Extended Application to Acetylcholinesterase Inhibitors
Bo-Han Su
,
Yi-Syuan Huang
,
Chia-Yun Chang
,
Y. Tu
,
Y. Tseng
Molecules
2013
Corpus ID: 18323297
There is a compelling need to discover type II inhibitors targeting the unique DFG-out inactive kinase conformation since they…
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2010
2010
Abstract P3-14-20: Phase 1 Dose-Escalation Study of the Investigational HER2/EGFR Inhibitor TAK-285 in Patients with Advanced Cancer
P. LoRusso
,
E. Chiorean
,
+7 authors
E. Sausville
2010
Corpus ID: 72748925
Background and Objectives: TAK-285 is a novel, orally active, dual HER2/EGFR inhibitor. Nonclinical data show that TAK-285 has…
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