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TAE226

National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
BACKGROUND AND PURPOSE Focal adhesion kinase (FAK), a main player in integrin signaling and survival, is frequently overexpressed… 
2009
2009
SummaryNeoangiogenesis plays an important role in tumor growth and metastasis. Evaluation of new anti-angiogenic targets may… 
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Highly Cited
2009
Highly Cited
2009
Focal adhesion kinase (FAK) is often up-regulated in a variety of malignancies, including gastrointestinal stromal tumor (GIST… 
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Highly Cited
2008
Highly Cited
2008
Focal Adhesion Kinase (FAK) is a non-receptor tyrosine kinase required for cell migration, proliferation and survival. FAK… 
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Highly Cited
2008
Highly Cited
2008
Focal adhesion kinase, FAK is a 125 kDa nonreceptor tyrosine kinase that localizes to focal adhesions. FAK is overexpressed in… 
Highly Cited
2008
Highly Cited
2008
Focal adhesion kinase (FAK) is a nonreceptor kinase that is overexpressed in many types of tumors. We developed a novel cancer… 
2008
2008
Purpose. Neuroblastoma is one of the most devastating pediatric solid tumors and is unresponsive to many interventions. TAE226 is… 
Highly Cited
2007
Highly Cited
2007
Glioblastomas are highly lethal cancers that resist current therapies. Novel therapies under development target molecular… 
Highly Cited
2007
Highly Cited
2007
Focal adhesion kinase (FAK) overexpression is frequently found in ovarian and other cancers and is predictive of poor clinical… 
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Highly Cited
2007
Highly Cited
2007
Multiple genetic aberrations in human gliomas contribute to their highly infiltrative and rapid growth characteristics. Focal… 
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