TAE226

 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
OBJECTIVES Focal adhesion kinase (FAK) overexpression is frequently found in invasive and metastatic cancers, but its role in… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2009
2009
BACKGROUND AND PURPOSE Focal adhesion kinase (FAK), a main player in integrin signaling and survival, is frequently overexpressed… (More)
Is this relevant?
2009
2009
Neoangiogenesis plays an important role in tumor growth and metastasis. Evaluation of new anti-angiogenic targets may broaden the… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2008
2008
PURPOSE Neuroblastoma is one of the most devastating pediatric solid tumors and is unresponsive to many interventions. TAE226 is… (More)
  • figure 2
  • figure 1
  • figure 3
  • figure 4
Is this relevant?
2008
2008
Focal adhesion kinase, FAK is a 125 kDa nonreceptor tyrosine kinase that localizes to focal adhesions. FAK is overexpressed in… (More)
Is this relevant?
Highly Cited
2008
Highly Cited
2008
Focal adhesion kinase (FAK) is a nonreceptor kinase that is overexpressed in many types of tumors. We developed a novel cancer… (More)
Is this relevant?
2008
2008
Focal Adhesion Kinase (FAK) is a non-receptor tyrosine kinase required for cell migration, proliferation and survival. FAK… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Glioblastomas are highly lethal cancers that resist current therapies. Novel therapies under development target molecular… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Focal adhesion kinase (FAK) overexpression is frequently found in ovarian and other cancers and is predictive of poor clinical… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Multiple genetic aberrations in human gliomas contribute to their highly infiltrative and rapid growth characteristics. Focal… (More)
Is this relevant?