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T-tubule organization

Known as: T-tubule organisation, T-tubule organization and biogenesis 
A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of the T-tubule. A… Expand
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

muscle cell developmentplasma membrane organization

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Mitsugumin 29 regulates t-tubule architecture in the failing heart
Transverse tubules (t-tubules) are uniquely-adapted membrane invaginations in cardiac myocytes that facilitate the synchronous… Expand
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2017
2017
CASAAV Technology to Examine Regulators of Heart Failure: Cause or Effect.
Clinicians understand heart failure (HF) as a syndrome which is characterized by a cluster of symptoms and signs that are the… Expand
2016
2016
High speed sCMOS‐based oblique plane microscopy applied to the study of calcium dynamics in cardiac myocytes
Oblique plane microscopy (OPM) is a form of light sheet microscopy that uses a single high numerical aperture microscope… Expand
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2015
2015
T-tubule disease: Relationship between t-tubule organization and regional contractile performance in human dilated cardiomyopathy.
Evidence from animal models suggest that t-tubule changes may play an important role in the contractile deficit associated with… Expand
2015
2015
Automatic quantitative analysis of t-tubule organization in cardiac myocytes using ImageJ.
The transverse tubule system in mammalian striated muscle is highly organized and contributes to optimal and homogeneous… Expand
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Highly Cited
2014
Highly Cited
2014
Variable t-tubule organization and Ca2+ homeostasis across the atria.
Although t-tubules have traditionally been thought to be absent in atrial cardiomyocytes, recent studies have suggested that t… Expand
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2013
2013
Synchrony of cardiomyocyte Ca(2+) release is controlled by T-tubule organization, SR Ca(2+) content, and ryanodine receptor Ca(2+) sensitivity.
Recent work has demonstrated that cardiomyocyte Ca(2+)release is desynchronized in several pathological conditions. Loss of Ca(2… Expand
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2013
2013
Inhibition of the late sodium current slows t-tubule disruption during the progression of hypertensive heart disease in the rat.
The treatment of heart failure (HF) is challenging and morbidity and mortality are high. The goal of this study was to determine… Expand
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2011
2011
PI3Ks Maintain the Structural Integrity of T-Tubules in Cardiac Myocytes
Background Phosphoinositide 3-kinases (PI3Ks) regulate numerous physiological processes including some aspects of cardiac… Expand
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2011
2011
Mechanisms of reduced contractility in an animal model of hypertensive heart failure
1. Alterations in intracellular Ca2+ homeostasis have frequently been implicated as underlying the contractile dysfunction of… Expand
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