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T-helper cell type 2

Known as: Type 2 Helper Cell, Th2 Cell, Type 2 T-helper cell 
Type 2 Helper Cells are a subset of helper-inducer T-lymphocytes which synthesize and secrete the interleukins IL-4, IL-5, IL-6, and IL-10. These… 
National Institutes of Health

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Broader (3)

CD4 Positive T LymphocytesHelper-Inducer T-LymphocyteT-Lymphocyte
Hematopoietic and Lymphoid TissueIL27RA protein, humanLymphoid TissueMicrobiological

Papers overview

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Highly Cited
2007
Highly Cited
2007
Inducible IL-12-producing B cells regulate Th2-mediated intestinal inflammation.
BACKGROUND & AIMS Our previous studies have identified a B-cell subset that is induced under inflammatory conditions in T-cell… 
Highly Cited
2003
Highly Cited
2003
Reduction of Serum Melatonin Levels in HIV-1-Infected Individuals’ Parallel Disease Progression: Correlation with Serum Interleukin-12 Levels
Abstract.Background:During the natural history of human immunodeficiency virus type I (HIV-1) infection, an impairment of… 
Highly Cited
1999
Highly Cited
1999
Upregulation of T-helper 1 cytokines and chemokine expression in post-transplant airway obliteration.
The major obstacle to long-term survival after lung transplantation is chronic graft dysfunction manifest as bronchiolitis… 
Highly Cited
1999
Highly Cited
1999
Genetic Control of Schistosome Infections by the SM1 Locus of the 5q31-q33 Region Is Linked to Differentiation of Type 2 Helper T Lymphocytes
ABSTRACT Human susceptibility to Schistosoma mansoni infections is controlled by the SM1 locus on chromosome 5 in q31-q33. This… 
Highly Cited
1997
Highly Cited
1997
Multiple Pathways for the Initiation of T Helper 2 (Th2) Responses
Since the initial descriptions of CD4+ T cell subsets with distinct functions and cytokine production profiles, the question of… 
Highly Cited
1997
Highly Cited
1997
Role of T helper 2 cells in intestinal goblet cell hyperplasia in mice infected with Trichinella spiralis.
BACKGROUND & AIMS The four principal types of intestinal epithelial cells are derived from multipotent stem cells. Currently… 
Highly Cited
1994
Highly Cited
1994
Antagonism of superantigen-stimulated helper T-cell clones and hybridomas by altered peptide ligand.
T-cell activation by an immunogenic peptide can be antagonized by nonstimulatory analogs of that peptide. We investigated this T… 
Highly Cited
1985
Highly Cited
1985
Both L3T4+ and Lyt-2+ helper T cells initiate cytotoxic T lymphocyte responses against allogenic major histocompatibility antigens but not against trinitrophenyl-modified self
This study characterizes the T helper (Th) cells that initiate primary cytotoxic T lymphocyte (CTL) responses against allogeneic… 
Highly Cited
1984
Highly Cited
1984
T cell-accessory cell interactions that initiate allospecific cytotoxic T lymphocyte responses: existence of both Ia-restricted and Ia-unrestricted cellular interaction pathways.
The specificity of the T-accessory cell interactions that initiate primary allospecific cytotoxic T lymphocyte (CTL) responses… 
Highly Cited
1978
Highly Cited
1978
Suppressor T-cell memory
MEMORY is a fundamental characteristic of immunological phenomena; it is manifested by enhanced responsiveness upon re-exposure… 
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