T-helper cell differentiation

Known as: helper T cell differentiation 
The process in which a relatively unspecialized thymocyte acquires specialized features of a T-helper cell. [GOC:ebc]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2018
051019902018

Papers overview

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Highly Cited
2013
Highly Cited
2013
Germinal centres support antibody affinity maturation and memory formation. Follicular T-helper cells promote proliferation and… (More)
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Highly Cited
2012
Highly Cited
2012
Follicular T-helper (T(FH)) cells cooperate with GL7(+)CD95(+) germinal center (GC) B cells to induce antibody maturation. Herein… (More)
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Highly Cited
2011
Highly Cited
2011
Helper T cells control host defense against pathogens. The receptors for interleukin 12 (IL-12), IL-4 and IL-6 are required for… (More)
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Highly Cited
2011
Highly Cited
2011
Regulatory T cells (Treg cells) are required for peripheral tolerance. Evidence indicates that Treg cells can adopt specialized… (More)
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Highly Cited
2010
Highly Cited
2010
Effective humoral immunity depends on the support of B cell responses by T follicular helper (Tfh) cells. Although it has been… (More)
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Highly Cited
2007
Highly Cited
2007
During differentiation of naive CD4+ helper T (TH) cells into effector cells, specific cytokine gene loci undergo extensive… (More)
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Highly Cited
2007
Highly Cited
2007
CD4(+) helper T cells can differentiate into several possible fates including: Th1, Th2, T regulatory, and Th17 cells. Although… (More)
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Highly Cited
2002
Highly Cited
2002
Different members of the Rel/NF-kappaB family may play different roles in immunity and inflammation. We report here that c-Rel… (More)
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Highly Cited
2000
Highly Cited
2000
On antigen challenge, T-helper cells differentiate into two functionally distinct subsets, Th1 and Th2, characterized by the… (More)
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Highly Cited
1999
Highly Cited
1999
The central role of type-2 helper T (Th2) cells in the development of allergic responses and immune responses against helminthic… (More)
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