T cell tolerance induction
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Multiple sclerosis is a T cell mediated chronic demyelinating disease of the central nervous system. Although currently available… Expand Summary The thymic medulla provides a specialized microenvironment for the negative selection of T cells, with the presence of… Expand The liver has a role in T cell tolerance induction, which is mainly achieved through the functions of tolerogenic hepatic antigen… Expand The liver is known to favor the induction of immunological tolerance rather than immunity. Although Kupffer cells (KC) have been… Expand Development of tumor‐specific T cell tolerance contributes to the failure of the immune system to eliminate tumor cells. Here we… Expand T cell tolerance can be induced by B cell presentation of Ags to naive T cells. To further characterize this mechanism of T cell… Expand