T Cell Transcription Factor 1

Known as: TCF7, TCF-7, TCF-1 Transcription Factor 
A TCF transcription factor that was originally identified as a DNA-binding protein that interacts with the enhancers of T-CELL RECEPTOR ALPHA GENES… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Group 2 innate lymphoid cells (ILC2) are innate lymphocytes that confer protective type 2 immunity during helminth infection and… (More)
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Highly Cited
2012
Highly Cited
2012
The TCF-1 and LEF-1 transcription factors are known to play critical roles in normal thymocyte development. Unexpectedly, we… (More)
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Highly Cited
2011
Highly Cited
2011
Although transcriptional programs associated with T-cell specification and commitment have been described, the functional… (More)
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Highly Cited
2010
Highly Cited
2010
T cell factor 1 (TCF-1) is a transcription factor known to act downstream of the canonical Wnt pathway and is essential for… (More)
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Highly Cited
2009
Highly Cited
2009
The differentiation of activated CD4+ T cells into the T helper type 1 (TH1) or TH2 fate is regulated by cytokines and the… (More)
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Highly Cited
2006
Highly Cited
2006
B cell differentiation is controlled by a complex network of lineage-restricted transcription factors. How perturbations to this… (More)
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Highly Cited
2002
Highly Cited
2002
Wnt signals regulate differentiation of neural crest cells through the beta-catenin associated with a nuclear mediator of the… (More)
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Highly Cited
2001
Highly Cited
2001
Constitutive activation of the Wnt signaling pathway is a root cause of many colon cancers. Activation of this pathway is caused… (More)
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Highly Cited
1998
Highly Cited
1998
Lymphoid enhancer factor 1 (LEF-1) and T cell factor 1 (TCF-1) are closely related transcription factors that are both expressed… (More)
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Highly Cited
1995
Highly Cited
1995
LYMPHOID enhancer-binding factor (LEF-1) and the closely related T-cell factor 1 (TCF-1) are sequence-specific and cell-type… (More)
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