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T-Cell Surface Glycoprotein CD5, human

Known as: Lymphocyte Antigen CD5, CD5, T-Cell Surface Glycoprotein CD5 
T-cell surface glycoprotein CD5 (495 aa, ~54 kDa) is encoded by the human CD5 gene. This protein may be involved in regulating the proliferation of T… Expand
National Institutes of Health

Papers overview

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2020
2020
CD5 B lymphocytes, also known as B1 cells, play key roles in the immune system. This subset of B cells is a focus of renewed… Expand
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Review
2019
Review
2019
Since its discovery, over 30 years ago, CD5 has been used as a marker to identify T cells, B1-a cells, and B cell chronic… Expand
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Review
2012
Review
2012
  • Leonard H. Sigal
  • Journal of clinical rheumatology : practical…
  • 2012
  • Corpus ID: 13220411
The full story of what surface markers mean about the cells on which they reside twists and turns as the days go by, with… Expand
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Review
2009
Review
2009
CD5 is a pan T cell marker also expressed at various developmental and activation stages on human B cells. CD5 is a well… Expand
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Highly Cited
2003
Highly Cited
2003
Ageing is characterized by numerous changes in lymphocyte subpopulations. In the present paper we have focused on B cells… Expand
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Highly Cited
2003
Highly Cited
2003
Physiologically, Ag detection by T cells occurs at the immunological synapse (IS) formed at the interface with an APC. CD5 is… Expand
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Highly Cited
2001
Highly Cited
2001
Current data indicate that CD5 functions as an inhibitor of TCR signal transduction. Consistent with this role, thymocyte… Expand
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1999
1999
CD5 is a 67 kDa type I glycoprotein which belongs to the Scavenger Receptor Cysteine-Rich (SRCR) family of receptors. This family… Expand
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Highly Cited
1999
Highly Cited
1999
The negative regulation of T- or B-cell antigen receptor signaling by CD5 was proposed based on studies of thymocytes and… Expand
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1996
1996
CD5 is a 67-kD glycoprotein that is expressed on most T lymphocytes and on a subset of mature B cells. Although its physiologic… Expand
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