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T-Cell Surface Glycoprotein CD5, human

Known as: Lymphocyte Antigen CD5, CD5, T-Cell Surface Glycoprotein CD5 
T-cell surface glycoprotein CD5 (495 aa, ~54 kDa) is encoded by the human CD5 gene. This protein may be involved in regulating the proliferation of T… 
National Institutes of Health

Papers overview

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2020
2020
CD5 B lymphocytes, also known as B1 cells, play key roles in the immune system. This subset of B cells is a focus of renewed… 
Review
2019
Review
2019
Since its discovery, over 30 years ago, CD5 has been used as a marker to identify T cells, B1‐a cells, and B cell chronic… 
Review
2012
Review
2012
  • L. Sigal
  • Journal of clinical rheumatology : practical…
  • 2012
  • Corpus ID: 13220411
AbstractThe full story of what surface markers mean about the cells on which they reside twists and turns as the days go by, with… 
Review
2009
Review
2009
  • A. Dalloul
  • Autoimmunity reviews
  • 2009
  • Corpus ID: 31174585
Highly Cited
2003
Highly Cited
2003
Highly Cited
2003
Highly Cited
2003
Physiologically, Ag detection by T cells occurs at the immunological synapse (IS) formed at the interface with an APC. CD5 is… 
Highly Cited
2001
Highly Cited
2001
Current data indicate that CD5 functions as an inhibitor of TCR signal transduction. Consistent with this role, thymocyte… 
1999
1999
CD5 is a 67 kDa type I glycoprotein which belongs to the Scavenger Receptor Cysteine-Rich (SRCR) family of receptors. This family… 
Highly Cited
1999
Highly Cited
1999
ABSTRACT The negative regulation of T- or B-cell antigen receptor signaling by CD5 was proposed based on studies of thymocytes… 
Highly Cited
1996
Highly Cited
1996
CD5 is a 67-kD glycoprotein that is expressed on most T lymphocytes and on a subset of mature B cells. Although its physiologic…