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T-Cell Receptor Activation
Known as:
T-Cell Receptor Interaction
, TCR Activation
, TCR Interaction
Any process in which a specific pair of interactions is observed between a T cell and an antigen-presenting cell, where the interactions include…
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National Institutes of Health
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Related topics
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16 relations
Antigen Presentation
B7 Transfected Melanoma Cell Vaccine
CD3D gene
CD3D protein, human
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
IL4‐induced gene 1 is secreted at the immune synapse and modulates TCR activation independently of its enzymatic activity
Aude Aubatin
,
Nouhoum Sako
,
X. Decrouy
,
E. Donnadieu
,
V. Molinier‐Frenkel
,
F. Castellano
European journal of immunology
2018
Corpus ID: 205793390
Amino‐acid catabolizing enzymes produced by mononuclear phagocytes play a central role in regulating the immune response. The…
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2015
2015
Role of acid sphingomyelinase bioactivity in human CD4+ T-cell activation and immune responses
A. Bai
,
E. Kokkotou
,
Y. Zheng
,
S. Robson
Cell Death and Disease
2015
Corpus ID: 17243030
Acid sphingomyelinase (ASM), a lipid hydrolase enzyme, has the potential to modulate various cellular activation responses via…
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Highly Cited
2013
Highly Cited
2013
CD73 expression on extracellular vesicles derived from CD4+CD25+Foxp3+ T cells contributes to their regulatory function
L. Smyth
,
K. Ratnasothy
,
+4 authors
G. Lombardi
European journal of immunology
2013
Corpus ID: 46384132
CD4+CD25+Foxp3+ Treg cells maintain immunological tolerance. In this study, the possibility that Treg cells control immune…
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2008
2008
Interplay between the heterotrimeric G-protein subunits Gαq and Gαi2 sets the threshold for chemotaxis and TCR activation
J. Ngai
,
M. Inngjerdingen
,
T. Berge
,
K. Taskén
BMC Immunology
2008
Corpus ID: 14457462
BackgroundTCR and CXCR4-mediated signaling appears to be reciprocally regulated pathways. TCR activation dampens the chemotactic…
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2004
2004
Cognate MHC–TCR interaction leads to apoptosis of antigen‐presenting cells
N. Setterblad
,
V. Blancheteau
,
+6 authors
N. Mooney
Journal of leukocyte biology
2004
Corpus ID: 5746339
Antigen presentation to T lymphocytes has been characterized extensively in terms of T lymphocyte activation and eventual cell…
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Highly Cited
2003
Highly Cited
2003
Human T lymphocytes transduced by lentiviral vectors in the absence of TCR activation maintain an intact immune competence.
S. Cavalieri
,
S. Cazzaniga
,
+4 authors
C. Bonini
Blood
2003
Corpus ID: 15508911
Gene transfer into T lymphocytes is currently being tested for the treatment of lymphohematologic disorders. We previously showed…
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Review
2002
Review
2002
Probing T cell membrane organization using dimeric MHC-Ig complexes.
T. Fahmy
,
J. Bieler
,
J. Schneck
Journal of immunological methods
2002
Corpus ID: 25240841
Highly Cited
2002
Highly Cited
2002
Growth and expansion of human T regulatory type 1 cells are independent from TCR activation but require exogenous cytokines
R. Bacchetta
,
C. Sartirana
,
M. Levings
,
C. Bordignon
,
S. Narula
,
M. Roncarolo
European journal of immunology
2002
Corpus ID: 35294637
Cloned T regulatory type 1 (Tr1) cells produce IL‐10, TGF‐β, IFN‐γ, and very low or non‐detectable levels of IL‐2 and IL‐4…
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2001
2001
Production of TNF-alpha by human V gamma 9V delta 2 T cells via engagement of Fc gamma RIIIA, the low affinity type 3 receptor for the Fc portion of IgG, expressed upon TCR activation by nonpeptidic…
V. Lafont
,
J. Liautard
,
J. Liautard
,
J. Favero
Journal of immunology
2001
Corpus ID: 45459635
Human lymphocytes expressing the gammadelta TCR represent a minor T cell subpopulation found in blood. The majority of these…
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Highly Cited
2000
Highly Cited
2000
A common E2F-1 and p73 pathway mediates cell death induced by TCR activation
N. A. Lissy
,
P. K. Davis
,
M. Irwin
,
W. Kaelin
,
S. Dowdy
Nature
2000
Corpus ID: 4430580
Strong stimulation of the T-cell receptor (TCR) on cycling peripheral T cells causes their apoptosis by a process called TCR…
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