T-47D

An adenocarcinoma cell line established from the pleural effusion of a 54 year old female patient with ductal breast carcinoma.
National Institutes of Health

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Highly Cited
2009
Highly Cited
2009
There is emerging evidence that the balance between estrogen receptor-alpha (ER(alpha)) and androgen receptor (AR) signaling is a… (More)
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Review
2004
Review
2004
The number of available breast cancer cell (BCC) lines is small, and only a very few of them have been extensively studied… (More)
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Highly Cited
2002
Highly Cited
2002
Cyclin D1 and cyclin E are overexpressed in approximately 45% and 30% of breast cancers, respectively, and adverse associations… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Obesity is a risk factor for breast cancer in postmenopausal women. As body weight and fat mass increase, circulating… (More)
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Highly Cited
2001
Highly Cited
2001
The mammalian target of rapamycin (mTOR) is a central regulator of G1 cell cycle protein synthesis that precedes commitment to… (More)
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Highly Cited
1998
Highly Cited
1998
The role of PRL in human breast tumorigenesis is not well understood. One of the limitations is the difficulty of accurately… (More)
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Highly Cited
1998
Highly Cited
1998
Human cytochromes P450 1A1 (CYP1A1) and P450 1B1 (CYP1B1) catalyze the metabolic activation of a number of procarcinogens and the… (More)
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Highly Cited
1993
Highly Cited
1993
Cyclins and proto-oncogenes including c-myc have been implicated in eukaryotic cell cycle control. The role of cyclins in… (More)
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1990
1990
Data are presented which document the first known effect of retinoic acid on progesterone receptor (PR) gene expression… (More)
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1987
1987
In order to determine growth effects of the progestin R5020, (promegestone), we have utilized the progesterone-receptor rich… (More)
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