Suramin

Known as: 1,3,5-Naphthalenetrisulfonic acid, 8,8'-(carbonylbis(imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino))bis-, Suramin [Chemical/Ingredient], 8,8'-[CARBONYLBIS[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bis-1,3,5-naphthalenetrisulfonic acid 
A polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors, including insulin-like… (More)
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
BACKGROUND Muscle strain injuries are extremely common in sports medicine. Muscle healing often is hindered by scar tissue… (More)
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Highly Cited
2003
Highly Cited
2003
Muscle injuries are very common in traumatology and sports medicine. Although muscle tissue can regenerate postinjury, the… (More)
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Review
2002
Review
2002
The induction of peripheral neuropathy is a common factor in limiting therapy with chemotherapeutic drugs. Little is known about… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Saphenous vein grafts are widely used for aortocoronary bypass surgery as treatment for severe atherosclerosis and… (More)
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Highly Cited
1996
Highly Cited
1996
The mitogen-activated protein kinase (MAPK) family is comprised of key regulatory proteins that control the cellular response to… (More)
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Highly Cited
1996
Highly Cited
1996
G protein alpha subunits expose specific binding sites that allow for the sequential, conformation-dependent binding of protein… (More)
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Review
1993
Review
1993
In the June 1992 edition of the Journal of Clinical Oncology, Myers el al. ( 1) reported on 38 cases of metastatic hormone… (More)
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Highly Cited
1992
Highly Cited
1992
The vascular endothelial growth factor (VEGF) family encompasses four polypeptides that result from alternative splicing of mRNA… (More)
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Highly Cited
1989
Highly Cited
1989
We administered suramin, an anti-parasitic drug and reverse transcriptase inhibitor, to 15 patients with metastatic cancer. This… (More)
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Highly Cited
1987
Highly Cited
1987
Suramin, a polyanionic compound, has previously been shown to dissociate platelet-derived growth factor (PDGF) from its receptor… (More)
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