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Mutations of human Cu,Zn superoxide dismutase (SOD) are found in about 20 percent of patients with familial amyotrophic lateral… Expand AMYOTROPHIC lateral sclerosis (ALS) is a degenerative disorder of motor neurons in the cortex, brainstem and spinal cord1,2. Its… Expand Superoxide dismutase reduces injury in many disease processes, implicating superoxide anion radical (O2-.) as a toxic species in… Expand This assay for superoxide dismutase (SOD, EC 220.127.116.11) activity involves inhibition of nitroblue tetrazolium reduction, with… Expand A simple and rapid method for the assay of superoxide dismutase in biological samples is described. Present method takes… Expand Shoots, roots, and seeds of corn (Zea mays L., cv. Michigan 500), oats (Avena sativa L., cv. Au Sable), and peas (Pisum sativum L… Expand The autoxidation of pyrogallol was investigated in the presence of EDTA in the pH range 7.9–10.6.
The rate of autoxidation… Expand Abstract The rate of autoxidation of epinephrine and the sensitivity of this autoxidation to inhibition by superoxide dismutase… Expand Nitro blue tetrazolium has been used to intercept O2− generated enzymically or photochemically. The reduction of NBT by O2− has… Expand Abstract An enzyme which catalyzes the dismutation of superoxide radicals (O2·- + O2·- + 2H+ → O2 + H2O2) has been purified by a… Expand