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Sulfinpyrazone

Known as: Sulphinpyrazone, 3,5-Pyrazolidinedione, 1,2-diphenyl-4-(2-(phenylsulfinyl)ethyl)-, Sulfoxyphenylpyrazolidine 
A phenylbutazone derivative with uricosuric and antithrombotic properties. Sulfinpyrazone competitively inhibits reabsorption of urate at the… Expand
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
Relatively few selective substrate and inhibitor probes have been identified for human UDP-glucuronosyltransferases (UGTs). This… Expand
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Highly Cited
2000
Highly Cited
2000
The multidrug resistance proteins MRP1 and MRP2 are members of the same subfamily of ATP-binding cassette transporters. Besides… Expand
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Review
1998
Review
1998
Accumulating evidence indicates that CYP2C9 ranks amongst the most important drug metabolizing enzymes in humans. Substrates for… Expand
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Highly Cited
1990
Highly Cited
1990
In previous papers we demonstrated that cyclosporin A (CsA) was specifically oxidized in rabbit and human liver by cytochrome P… Expand
Highly Cited
1988
Highly Cited
1988
Tolbutamide hydroxylation has been investigated in human liver microsomes. Anti-human liver NADPH-cytochrome P-450 reductase IgG… Expand
Highly Cited
1988
Highly Cited
1988
The neuroblastoma-like cell line N2A and the pheochromocytoma-like cell line PC12 excrete about 20-25% of the intracellular… Expand
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Highly Cited
1988
Highly Cited
1988
To determine whether specific antiplatelet therapies improved vein graft patency after coronary artery bypass grafting (CABG) we… Expand
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Highly Cited
1985
Highly Cited
1985
We performed a randomized, double-blind, placebo-controlled trial in 555 patients with unstable angina who were hospitalized in… Expand
Highly Cited
1983
Highly Cited
1983
The effect of sulfinpyrazone on endothelial injury induced by homocysteine has been studied both in vitro, using cultured human… Expand
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Highly Cited
1978
Highly Cited
1978
  • The New England journal of medicine
  • 1978
  • Corpus ID: 10267616
Five hundred and eighty-five patients with threatened stroke were followed in a randomized clinical trial for an average of 26… Expand