Sulfinpyrazone

Known as: Sulphinpyrazone, 3,5-Pyrazolidinedione, 1,2-diphenyl-4-(2-(phenylsulfinyl)ethyl)-, Sulfoxyphenylpyrazolidine 
A phenylbutazone derivative with uricosuric and antithrombotic properties. Sulfinpyrazone competitively inhibits reabsorption of urate at the… (More)

Topic mentions per year

Topic mentions per year

1960-2016
0204019602016

Papers overview

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Highly Cited
2006
Highly Cited
2006
Relatively few selective substrate and inhibitor probes have been identified for human UDP-glucuronosyltransferases (UGTs). This… (More)
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Highly Cited
2002
Highly Cited
2002
Induction of cytochrome P450 3A4 (CYP3A4) is determined typically by employing primary culture of human hepatocytes and measuring… (More)
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Highly Cited
2000
Highly Cited
2000
The multidrug resistance proteins MRP1 and MRP2 are members of the same subfamily of ATP-binding cassette transporters. Besides… (More)
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Highly Cited
2000
Highly Cited
2000
The human multidrug resistance protein MRP1 and its homolog, MRP2, are both suggested as being involved in cancer drug resistance… (More)
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Highly Cited
1988
Highly Cited
1988
Tolbutamide hydroxylation has been investigated in human liver microsomes. Anti-human liver NADPH-cytochrome P-450 reductase IgG… (More)
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Highly Cited
1988
Highly Cited
1988
To determine whether specific antiplatelet therapies improved vein graft patency after coronary artery bypass grafting (CABG) we… (More)
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Highly Cited
1985
Highly Cited
1985
We performed a randomized, double-blind, placebo-controlled trial in 555 patients with unstable angina who were hospitalized in… (More)
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1983
1983
The effect of sulfinpyrazone on endothelial injury induced by homocysteine has been studied both in vitro, using cultured human… (More)
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1980
1980
The disposition and metabolism of sulfinpyrazone have been studied after oral administration of 100 mg 14C-labelled drug to two… (More)
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1975
1975
The absorption, biotransformation and elimination of sulfinpyrazone, 1,2-diphenyl-3,5-dioxo-4-(2′-phenylsufinylethyl… (More)
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