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Sulfinpyrazone

Known as: Sulphinpyrazone, 3,5-Pyrazolidinedione, 1,2-diphenyl-4-(2-(phenylsulfinyl)ethyl)-, Sulfoxyphenylpyrazolidine 
A phenylbutazone derivative with uricosuric and antithrombotic properties. Sulfinpyrazone competitively inhibits reabsorption of urate at the… 
National Institutes of Health

Related topics

Related topics

20 relations
Angina PectorisAntipyrineCoronary heart diseaseDrug Allergy

Narrower (2)

AnturaneG 25671

Broader (1)

Uricosuric Agents

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
Medical adjuvant treatment to increase patency of arteriovenous fistulae and grafts.
BACKGROUND End-stage renal disease (ESRD) patients often require either the formation of an arteriovenous (AV) fistula or an AV… 
Highly Cited
1996
Highly Cited
1996
Ascorbate Uptake by Microvascular Endothelial Cells of Rat Skeletal Muscle
Objective: In several systems, exogenous ascorbate (reduced vitamin C) has been shown to protect against microvascular injury… 
Review
1988
Review
1988
Trends in physician management of uncomplicated acute myocardial infarction, 1970 to 1987.
Review
1987
Review
1987
The St. Jude Medical cardiac valve in infants and children: role of anticoagulant therapy.
Highly Cited
1987
Highly Cited
1987
The amplified chemiluminescence test to characterize antirheumatic drugs as oxygen radical scavengers.
1982
1982
In Vivo Platelet Activation Following Myocardial Infarction and Acute Coronary Ischaemia
Summary Forty-seven patients presenting with acute chest pain had in vivo platelet activity assessed by measuring plasma levels… 
Highly Cited
1979
Highly Cited
1979
The Effect of Agents which Modify Platelet Behaviour and of Magnesium Ions on Thrombus Formation In Vivo
Summary The ability of potential anti-thrombotic agents to modify platelet-thrombus formation in injured cerebral arteries in the… 
Highly Cited
1978
Highly Cited
1978
EFFECTS OF SULPHINPYRAZONE AND ASPIRIN ON PROSTAGLANDIN I2 (PROSTACYCLIN) SYNTHESIS BY ENDOTHELIAL CELLS
Synthesis of prostaglandin I2, (PGI2, prostacyclin) by vascular endothelium (assayed by the ability of cultured endothelial cells… 
Highly Cited
1975
Highly Cited
1975
The Role of Sulfinpyrazone in the Prevention of Arterio‐venous Shunt Thrombosis
The effect of sulfinpyrazone on the incidence of thrombosis of arterio-venous shunts was investigated in a double-blind crossover… 
Highly Cited
1967
Highly Cited
1967
The effect of sulfinpyrazone on platelet economy and thrombus formation in rabbits.
Platelet survival was prolonged in rabbits which had been on sulfinpyrazone for 30 days or more. This was not accompanied by… 
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