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Sulfasalazine

Known as: 5-((P-(2-Pyridylsulfamoyl)phenyl)azo)salicylic acid, Sulphasalazine, Salazosulfapyridine 
A synthetic salicylic acid derivative with affinity for connective tissues containing elastin and formulated as a prodrug, antiinflammatory… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Currently, medications used to treat rheumatoid arthritis (RA) are glucocorticoids (GCs) and nonsteroidal anti‐inflammatory drugs… Expand
Review
2019
Review
2019
Most patients with ulcerative colitis (UC) have mild-to-moderate disease activity, with low risk of colectomy, and are managed by… Expand
Highly Cited
1999
Highly Cited
1999
BACKGROUND The treatment of rheumatoid arthritis should aim at clinical remission. This multicentre, randomised trial with 2-year… Expand
Highly Cited
1998
Highly Cited
1998
Transcription factors of the NF-kappaB/Rel family are critical for inducible expression of multiple genes involved in… Expand
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Highly Cited
1997
Highly Cited
1997
BACKGROUND The value of intensive combination therapy in early rheumatoid arthritis is unproven. In a multicentre, double-blind… Expand
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Highly Cited
1996
Highly Cited
1996
BACKGROUND Rheumatoid arthritis is a common disease that causes substantial morbidity and mortality. The responses of patients… Expand
Highly Cited
1996
Highly Cited
1996
OBJECTIVE To determine whether sulfasalazine (SSZ) at a dosage of 2,000 mg/day is effective for the treatment of active psoriatic… Expand
Highly Cited
1989
Highly Cited
1989
OBJECTIVE--To assess the safety and efficacy of a preparation of mesalazine (5-aminosalicylic acid) coated with a pH dependent… Expand
Highly Cited
1980
Highly Cited
1980
We studied the therapeutic efficacy of sulfasalazine and its metabolites sulfapyridine and 5-aminosalicylic acid in nine patients… Expand
Highly Cited
1977
Highly Cited
1977
Sulphasalazine (S.A.S.P.) is of proven value in the treatment of ulcerative colitis, but its mode of action is unknown. When it… Expand