Sulfasalazine

Known as: 5-((P-(2-Pyridylsulfamoyl)phenyl)azo)salicylic acid, Sulphasalazine, Salazosulfapyridine 
A synthetic salicylic acid derivative with affinity for connective tissues containing elastin and formulated as a prodrug, antiinflammatory… (More)

Topic mentions per year

Topic mentions per year

1948-2017
05010015019482016

Papers overview

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Review
2016
Review
2016
The crucial issue for a better pregnancy outcome in women with autoimmune rheumatic diseases is appropriate planning, with… (More)
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Highly Cited
2006
Highly Cited
2006
Stools from 109 patients with inflammatory bowel disease (13.4%) contained Clostridium difficile or its toxin, an incidence… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND & AIMS Activation of NF-kappaB/Rel has been implicated in the pathogenesis of inflammatory bowel disease (IBD… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND The treatment of rheumatoid arthritis should aim at clinical remission. This multicentre, randomised trial with 2-year… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Phase II trials of leflunomide, an inhibitor of de-novo pyrimidine synthesis, have shown efficacy in rheumatoid… (More)
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Highly Cited
1998
Highly Cited
1998
Transcription factors of the NF-kappaB/Rel family are critical for inducible expression of multiple genes involved in… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND The value of intensive combination therapy in early rheumatoid arthritis is unproven. In a multicentre, double-blind… (More)
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Highly Cited
1996
Highly Cited
1996
BACKGROUND Rheumatoid arthritis is a common disease that causes substantial morbidity and mortality. The responses of patients… (More)
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Highly Cited
1989
Highly Cited
1989
OBJECTIVE To assess the safety and efficacy of a preparation of mesalazine (5-aminosalicylic acid) coated with a pH dependent… (More)
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Highly Cited
1977
Highly Cited
1977
Sulphasalazine (S.A.S.P.) is of proven value in the treatment of ulcerative colitis, but its mode of action is unknown. When it… (More)
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