Sulfaphenazole

Known as: Sulfafenazol, N'-(1-phenylpyrazol-5-yl)sulfanilamide, Sulfaphenylpyrazol 
A long-acting sulfonamide antibiotic used in the treatment of leprosy.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Previously, we showed that sulfaphenazole (SUL), an antimicrobial agent that is a potent inhibitor of cytochrome P4502C9, is… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2005
Highly Cited
2005
TRPV4 is a broadly expressed Ca2+-permeable cation channel in the vanilloid subfamily of transient receptor potential channels… (More)
  • figure 1
  • figure 3
  • figure 2
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Voriconazole is a triazole antifungal agent with potent activity against a broad spectrum of clinically significant pathogens. In… (More)
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • table 2
Is this relevant?
Highly Cited
2001
Highly Cited
2001
In the porcine coronary artery, a cytochrome P450 (CYP) isozyme homologous to CYP 2C8/9 has been identified as an endothelium… (More)
  • figure 1
  • figure 3
  • figure 2
  • figure 4
  • figure 5
Is this relevant?
2001
2001
OBJECTIVE The present study was carried out to identify the cytochrome P450 enzyme(s) involved in the 6-hydroxylation and O… (More)
Is this relevant?
Highly Cited
1999
Highly Cited
1999
AIMS To investigate the kinetics of CYP-mediated N-demethylation of methadone in human liver microsomes, and examine the role of… (More)
  • figure 2
  • figure 3
  • figure 4
  • table 1
Is this relevant?
Highly Cited
1999
Highly Cited
1999
The contributions of specific human liver cytochrome P-450 (CYP) enzymes to the activation, via 4-hydroxylation, of the… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Review
1998
Review
1998
Accumulating evidence indicates that CYP2C9 ranks amongst the most important drug metabolizing enzymes in humans. Substrates for… (More)
  • figure 1
  • figure 2
  • table 2
Is this relevant?
Highly Cited
1998
Highly Cited
1998
There is a need for methodology to predict clinically significant drug-drug interactions so that clinical studies can be directed… (More)
  • table 1
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
1997
Highly Cited
1997
4-Hydroxylation is an important pathway of tamoxifen metabolism because the product of this reaction is intrinsically 100 times… (More)
Is this relevant?