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Sulfaphenazole

Known as: Sulfafenazol, N'-(1-phenylpyrazol-5-yl)sulfanilamide, Sulfaphenylpyrazol 
A long-acting sulfonamide antibiotic used in the treatment of leprosy.
National Institutes of Health

Papers overview

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Highly Cited
2000
Highly Cited
2000
Carboxychroman metabolites of the major dietary tocopherols are excreted in human urine, but the mechanism of their synthesis is… Expand
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Highly Cited
1999
Highly Cited
1999
AIMS To identify the human cytochrome P450 enzyme(s) involved in the in vitro metabolism of rosiglitazone, a potential oral… Expand
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Review
1998
Review
1998
Accumulating evidence indicates that CYP2C9 ranks amongst the most important drug metabolizing enzymes in humans. Substrates for… Expand
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Highly Cited
1998
Highly Cited
1998
AIMS Chemical inhibitors of cytochrome P450 (CYP) are a useful tool in defining the role of individual CYPs involved in drug… Expand
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Highly Cited
1997
Highly Cited
1997
4-Hydroxylation is an important pathway of tamoxifen metabolism because the product of this reaction is intrinsically 100 times… Expand
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Highly Cited
1996
Highly Cited
1996
1. We evaluated the specificity of 15 substrates and 14 inhibitors of the cytochrome P450s using nine human P450 forms expressed… Expand
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Highly Cited
1995
Highly Cited
1995
1. The potential of ketoconazole and sulphaphenazole to inhibit specific P450 enzyme activities (1A2, 2A6, 2B6, 2C9/8, 2C19, 2D6… Expand
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Highly Cited
1995
Highly Cited
1995
Identifying selective inhibitors of cytochrome P450 isoforms is a useful tool in defining the role of individual cytochrome P450s… Expand
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Highly Cited
1992
Highly Cited
1992
Previous kinetic studies have identified a high-affinity (S)-warfarin 7-hydroxylase present in human liver microsomes which… Expand
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Highly Cited
1991
Highly Cited
1991
A human cytochrome P4502C9 cDNA clone has been isolated from a human liver bacteriophage Lambda gt11 library using… Expand
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