Succinate Dehydrogenase Assembly Factor 2, Mitochondrial Protein

Known as: SDH Assembly Factor 2, SDH5, SDHAF2 
Succinate dehydrogenase assembly factor 2, mitochondrial (166 aa, ~20 kDa) is encoded by the human SDHAF2 gene. This protein is involved in the… (More)
National Institutes of Health

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Highly Cited
2014
Highly Cited
2014
CONTEXT Pheochromocytomas and paragangliomas have a highly diverse genetic background, with a third of the cases carrying a… (More)
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2013
2013
Mitochondria complex II (succinate dehydrogenase, SDH) plays a central role in respiratory metabolism as a component of both the… (More)
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Highly Cited
2012
Highly Cited
2012
Germline mutations in the RET, SDHA, SDHAF2, SDHB, SDHC, SDHD, MAX, TMEM127, NF1 or VHL genes are identified in about 30% of… (More)
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2012
2012
Pheochromocytomas are neuroendocrine tumors of the adrenal medulla which can occur either sporadically or in the context of… (More)
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Highly Cited
2011
Highly Cited
2011
Pheochromocytomas and paragangliomas are neuroendocrine tumors that occur in the context of inherited cancer syndromes in ∼30% of… (More)
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2011
2011
PURPOSE Hereditary head and neck paraganglioma (HNPGL) syndromes are associated with mutations in the SDHD(PGL1), SDHC(PGL3), and… (More)
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Highly Cited
2010
Highly Cited
2010
Mitochondrial succinate-coenzyme Q reductase (complex II) consists of four subunits, SDHA, SDHB, SDHC and SDHD. Heterozygous… (More)
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Highly Cited
2010
Highly Cited
2010
CONTEXT Paragangliomas and pheochromocytomas are neuroendocrine tumors that occur sporadically and in the context of inherited… (More)
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Review
2010
Review
2010
The past decade has seen a revival of interest in the metabolic adaptations of tumours, named for their original discoverer, Otto… (More)
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Highly Cited
2009
Highly Cited
2009
Mammalian mitochondria contain about 1100 proteins, nearly 300 of which are uncharacterized. Given the well-established role of… (More)
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