Substantia nigra structure
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Parkinson's disease (PD) is a neurodegenerative disorder characterized by degeneration of dopaminergic neurons in the substantia… Expand Parkinson's disease (PD) results primarily from the death of dopaminergic neurons in the substantia nigra. Current PD medications… Expand Parkinson's disease is a common neurodegenerative disease with complex clinical features. Autosomal recessive juvenile… Expand Abstract: Radicals are species containing one or more unpaired electrons, such as nitric oxide (NO•−). The oxygen radical… Expand The micro-architecture of the substantia nigra was studied in control cases of varying age and patients with parkinsonism. A… Expand The striatum, which is the major component of the basal ganglia in the brain, is regulated in part by dopaminergic input from the… Expand The Lewy body is a distinctive neuronal inclusion that is always found in the substantia nigra and other specific brain regions… Expand We detected large numbers of HLA-DR-positive reactive microglia (macrophages), along with Lewy bodies and free melanin, in the… Expand Four persons developed marked parkinsonism after using an illicit drug intravenously. Analysis of the substance injected by two… Expand Abstract The localization and distribution of serotonin (5-hydroxytryptamine, 5-HT) has been studied with the indirect… Expand