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Substantia nigra structure
Known as:
Substantia nigra
, Nucleus of basis pedunculi
, Nigras, Substantia
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A large cell mass extending forward, over the dorsal surface of the crus cerebri, from the rostral border of the pons into the subthalamic region. It…
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National Institutes of Health
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Related topics
Related topics
22 relations
Broader (1)
Basal Ganglia
Blood supply aspects
Body part
Brain
CDISC SDTM Anatomical Location Terminology
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Narrower (1)
Pars Compacta
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Hereditary Early-Onset Parkinson's Disease Caused by Mutations in PINK1
E. Valente
,
P. Abou-Sleiman
,
+19 authors
N. Wood
Science
2004
Corpus ID: 33630092
Parkinson's disease (PD) is a neurodegenerative disorder characterized by degeneration of dopaminergic neurons in the substantia…
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Highly Cited
2004
Highly Cited
2004
The new mutation, E46K, of α‐synuclein causes parkinson and Lewy body dementia
J. Zarranz
,
Javier Alegre
,
+12 authors
J. D. de Yébenes
Annals of neurology
2004
Corpus ID: 55263
Familial parkinsonism and dementia with cortical and subcortical Lewy bodies is uncommon, and no genetic defect has been reported…
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Review
2003
Review
2003
Parkinson's Disease Mechanisms and Models
W. Dauer
,
S. Przedborski
Neuron
2003
Corpus ID: 10400095
Highly Cited
1998
Highly Cited
1998
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
T. Kitada
,
S. Asakawa
,
+6 authors
N. Shimizu
Nature
1998
Corpus ID: 4432261
Parkinson's disease is a common neurodegenerative disease with complex clinical features. Autosomal recessive juvenile…
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Review
1992
Review
1992
Reactive Oxygen Species and the Central Nervous System
B. Halliwell
Journal of neurochemistry
1992
Corpus ID: 77937
Abstract: Radicals are species containing one or more unpaired electrons, such as nitric oxide (NO•−). The oxygen radical…
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Highly Cited
1991
Highly Cited
1991
Ageing and Parkinson's disease: substantia nigra regional selectivity.
J. Fearnley
,
A. Lees
Brain : a journal of neurology
1991
Corpus ID: 17487837
The micro-architecture of the substantia nigra was studied in control cases of varying age and patients with parkinsonism. A…
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Highly Cited
1990
Highly Cited
1990
D1 and D2 dopamine receptor-regulated gene expression of striatonigral and striatopallidal neurons.
C. Gerfen
,
T. Engber
,
+4 authors
D. Sibley
Science
1990
Corpus ID: 46195338
The striatum, which is the major component of the basal ganglia in the brain, is regulated in part by dopaminergic input from the…
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Review
1988
Review
1988
The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease.
W. Gibb
,
A. Lees
Journal of neurology, neurosurgery, and…
1988
Corpus ID: 15172915
The Lewy body is a distinctive neuronal inclusion that is always found in the substantia nigra and other specific brain regions…
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Highly Cited
1988
Highly Cited
1988
Reactive microglia are positive for HLA‐DR in the substantia nigra of Parkinson's and Alzheimer's disease brains
P. Mcgeer
,
S. Itagaki
,
B. Boyes
,
E. Mcgeer
Neurology
1988
Corpus ID: 31229795
We detected large numbers of HLA-DR-positive reactive microglia (macrophages), along with Lewy bodies and free melanin, in the…
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Highly Cited
1983
Highly Cited
1983
Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis.
J. Langston
,
P. Ballard
,
J. Tetrud
,
I. Irwin
Science
1983
Corpus ID: 31966839
Four persons developed marked parkinsonism after using an illicit drug intravenously. Analysis of the substance injected by two…
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