Structure of primordial sex cell

Known as: Gonocyte, Primitive germ cell, Primordial Germ Cell 
A mesodermal precursor of germ cells, detectable at four weeks of fetal development. It originates in the allantois and then migrates through the… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1966-2018
0204019662018

Papers overview

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Highly Cited
2011
Highly Cited
2011
The generation of properly functioning gametes in vitro requires reconstitution of the multistepped pathway of germ cell… (More)
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Highly Cited
2009
Highly Cited
2009
The rarity and inaccessibility of the earliest primordial germ cells (PGCs) in the mouse embryo thwart efforts to investigate… (More)
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Highly Cited
2009
Highly Cited
2009
The leading cause of infertility in men and women is quantitative and qualitative defects in human germ-cell (oocyte and sperm… (More)
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Highly Cited
2008
Highly Cited
2008
Primordial germ cell (PGC) migration in zebrafish is directed by the chemokine SDF-1a that activates its receptor CXCR4b. Little… (More)
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Highly Cited
2005
Highly Cited
2005
Germ cell fate in mice is induced in pluripotent epiblast cells in response to signals from extraembryonic tissues. The… (More)
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Highly Cited
2004
Highly Cited
2004
Egg and sperm cells (gametes) of the mouse are derived from a founder population of primordial germ cells that are set aside… (More)
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Highly Cited
2003
Highly Cited
2003
Genome-wide epigenetic reprogramming by demethylation occurs in early mouse embryos and primordial germ cells. In early embryos… (More)
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Highly Cited
2002
Highly Cited
2002
The signals directing primordial germ cell (PGC) migration in vertebrates are largely unknown. We demonstrate that sdf-1 mRNA is… (More)
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Highly Cited
1999
Highly Cited
1999
In many organisms the allocation of primordial germ cells (PGCs) is determined by the inheritance of maternal factors deposited… (More)
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Highly Cited
1981
Highly Cited
1981
Primitive-streak-stage mouse embryos were treated with Mitomycin C injected intraperitoneally into pregnant females at 6.75--7.0… (More)
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