Sterol Regulatory Element Binding Protein 1a

Known as: SREBP 1a, SREBP-1a 
SREBP1-A is an isoform of sterol regulatory element binding protein 1 that is a potent activator of GENETIC TRANSCRIPTION. It is the predominant form… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1993-2018
05101519932018

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Sterol regulatory element-binding proteins (SREBPs) are a family of membrane-bound transcription factors that regulate… (More)
  • figure 1
  • table I
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Two treatments, fasting/refeeding and administration of liver X receptor (LXR) agonists, elevate the mRNA for sterol regulatory… (More)
Is this relevant?
Highly Cited
2000
Highly Cited
2000
The liver X receptors (LXRs) are members of the nuclear hormone receptor superfamily that are bound and activated by oxysterols… (More)
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Dietary fish oil induces hepatic peroxisomal and microsomal fatty acid oxidation by peroxisome proliferator-activator receptor… (More)
Is this relevant?
Highly Cited
1998
Highly Cited
1998
We produced transgenic mice that express a dominant-positive truncated form of sterol regulatory element-binding protein-2 (SREBP… (More)
  • figure 1
  • table I
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
1998
1998
BACKGROUND The sterol regulatory element binding proteins (SREBPs) are helix-loop-helix transcriptional activators that control… (More)
Is this relevant?
Highly Cited
1997
Highly Cited
1997
We have produced transgenic mice whose livers express a dominant positive NH2-terminal fragment of sterol regulatory element… (More)
  • figure 1
  • figure 2
  • table I
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1997
Highly Cited
1997
The 5' end of the mRNA-encoding sterol regulatory element binding protein-1 (SREBP-1) exists in two forms, designated 1a and 1c… (More)
  • table I
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1996
Highly Cited
1996
The NH2-terminal domain of sterol-regulatory element binding protein-1a (SREBP-1a) activates transcription of genes encoding… (More)
  • table I
  • table II
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
1993
Highly Cited
1993
We report the cDNA cloning of SREBP-2, the second member of a family of basic-helix-loop-helix-leucine zipper (bHLH-Zip… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?