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Sterol Regulatory Element Binding Protein 1a

Known as: SREBP 1a, SREBP-1a 
SREBP1-A is an isoform of sterol regulatory element binding protein 1 that is a potent activator of GENETIC TRANSCRIPTION. It is the predominant form… Expand
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
We show that mice with a targeted deficiency in the gene encoding the lipogenic transcription factor SREBP-1a are resistant to… Expand
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Review
2004
Review
2004
Sterol regulatory element binding proteins (SREBPs) are a family of transcription factors that regulate lipid homeostasis by… Expand
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Highly Cited
2004
Highly Cited
2004
Androgen ablation, the most common therapeutic treatment used for advanced prostate cancer, triggers the apoptotic regression of… Expand
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Highly Cited
2003
Highly Cited
2003
The synthesis of fatty acids and cholesterol, the building blocks of membranes, is regulated by three membrane-bound… Expand
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Highly Cited
2003
Highly Cited
2003
Sterol regulatory element-binding proteins (SREBPs) are a family of membrane-bound transcription factors that regulate… Expand
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Highly Cited
2002
Highly Cited
2002
Two treatments, fasting/refeeding and administration of liver X receptor (LXR) agonists, elevate the mRNA for sterol regulatory… Expand
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Review
2002
Review
2002
Sterol regulatory element-binding proteins (SREBPs) have been established as lipid synthetic transcription factors for… Expand
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Highly Cited
2001
Highly Cited
2001
The reduction in hepatic abundance of sterol regulatory element binding protein-1 (SREBP-1) mRNA and protein associated with the… Expand
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Highly Cited
1997
Highly Cited
1997
We have produced transgenic mice whose livers express a dominant positive NH2-terminal fragment of sterol regulatory element… Expand
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Highly Cited
1993
Highly Cited
1993
We report the cDNA cloning of SREBP-2, the second member of a family of basic-helix-loop-helix-leucine zipper (bHLH-Zip… Expand
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