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Sterol Regulatory Element Binding Protein 1a

Known as: SREBP 1a, SREBP-1a 
SREBP1-A is an isoform of sterol regulatory element binding protein 1 that is a potent activator of GENETIC TRANSCRIPTION. It is the predominant form… Expand
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
We show that mice with a targeted deficiency in the gene encoding the lipogenic transcription factor SREBP-1a are resistant to… Expand
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Review
2004
Review
2004
Sterol regulatory element binding proteins (SREBPs) are a family of transcription factors that regulate lipid homeostasis by… Expand
Highly Cited
2003
Highly Cited
2003
The synthesis of fatty acids and cholesterol, the building blocks of membranes, is regulated by three membrane-bound… Expand
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Highly Cited
2003
Highly Cited
2003
Sterol regulatory element-binding proteins (SREBPs) are a family of membrane-bound transcription factors that regulate… Expand
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Highly Cited
2002
Highly Cited
2002
Two treatments, fasting/refeeding and administration of liver X receptor (LXR) agonists, elevate the mRNA for sterol regulatory… Expand
Highly Cited
2001
Highly Cited
2001
The reduction in hepatic abundance ofsterol regulatory element binding protein-1(SREBP-1) mRNA and protein associated with the… Expand
Highly Cited
2000
Highly Cited
2000
The classic sterol regulatory cis element (sre-1) in the LDL receptor promoter mediates sterol regulatory element binding protein… Expand
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Highly Cited
1997
Highly Cited
1997
We have produced transgenic mice whose livers express a dominant positive NH2-terminal fragment of sterol regulatory element… Expand
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Highly Cited
1996
Highly Cited
1996
The NH2-terminal domain of sterol-regulatory element binding protein-1a (SREBP-1a) activates transcription of genes encoding… Expand
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Highly Cited
1993
Highly Cited
1993
We report the cDNA cloning of SREBP-2, the second member of a family of basic-helix-loop-helix-leucine zipper (bHLH-Zip… Expand
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