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Sterol 26-Hydroxylase, Mitochondrial

Known as: Cholestanetriol 26-Monooxygenase, Cytochrome P450 27A1, Sterol 27-hydroxylase 
Sterol 26-hydroxylase, mitochondrial (531 aa, ~60 kDa) is encoded by the human CYP27A1 gene. This protein is involved in cholesterol homeostasis and… 
National Institutes of Health

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7 relations
CYP27A1 geneEnzyme GeneHemeproteinsMetabolic Detoxication, Drug

Papers overview

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2013
2013
Posttranslational modification by an isolevuglandin diminishes activity of the mitochondrial cytochrome P450 27A1[S]
Posttranslational modification by isolevuglandins (isoLGs), arachidonate oxidation products, is an important yet understudied… 
2008
2008
Studies of Membrane Topology of Mitochondrial Cholesterol Hydroxylases CYPs 27A1 and 11A1
Mitochondrial cytochrome P450 enzymes (CYP or P450, EC 1.14.13.15) play an important role in metabolism of cholesterol. CYP27A1… 
2004
2004
Studies on sterol 27-hydroxylase (CYP27A1)
Human sterol 27-hydroxylase (CYP27A1) has been studied in the present thesis with focus on substrate specificity and possible… 
2003
2003
3P-0716 Expression and regulation of sterol 27-hydroxylase (CYP27A1) in human macrophages
2000
2000
Sterol 27-hydroxylase is a tissue specific regulator of cholesterol and bile acid synthesis
1968
1968
Formation of bile acids in man: conversion of cholesterol into 5-beta-cholestane-3-alpha, 7-alpha, 12-alpha-triol in liver homogenates.
The mechanisms of the conversion of cholesterol into bile acids in man were studied by examining the metabolism of cholesterol-1… 
1966
1966
The oxidation of 5-beta-cholestane-3-alpha, 7-alpha, 12-alpha, 26-tetraol to 5-beta-cholestane-3-alpha, 7-alpha, 12-alpha-triol-26-oic acid via 5-beta-cholestane-3-alpha, 7-alpha, 12-alpha-triol-26…
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