Steroidal Aromatase Inhibitor

Known as: Steroidal Androstenedione Aromatase Inhibitors, Steroidal Estrogen Synthase Inhibitors, Steroidal Estrogen Synthetase Inhibitors 
An aromatase inhibitor with a steroidal structure. Steroidal aromatase inhibitors work by forming a permanent bond with the enzyme.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1946-2017
0204019462016

Papers overview

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Highly Cited
2005
Highly Cited
2005
New chemical entities, steroidal C-17 benzoazoles (5, 6, 9 and 10) and pyrazines (14 and 15) were rationally designed and… (More)
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2004
2004
The irreversible steroidal aromatase inhibitor exemestane (EXE) is one of three third generation aromatase inhibitors currently… (More)
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Highly Cited
1998
Highly Cited
1998
The effect of exemestane (6-methylenandrosta-1,4-diene-3,17-dione) 25 mg p.o. once daily on in vivo aromatization was studied in… (More)
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Highly Cited
1997
Highly Cited
1997
Clinical and endocrinological effects of exemestane (6-methylenandrosta-1,4-diene-3,17-dione; PNU 155971) were evaluated in an… (More)
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Highly Cited
1996
Highly Cited
1996
The effect of anastrozole ('Arimidex', ZD1033), a new, selective, non-steroidal aromatase inhibitor on in vivo aromatisation and… (More)
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Highly Cited
1996
Highly Cited
1996
Cyclin-dependent kinases (Cdk) act to regulate G1- to S-phase transition in mammalian cells. We have studied the effects of… (More)
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1995
1995
The androstenedione derivative, exemestane (FCE 24304), is a new orally active irreversible aromatase inhibitor. Fifty-six post… (More)
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Highly Cited
1993
Highly Cited
1993
The development of resistance to the antiestrogen tamoxifen occurs in a high percentage of initially responsive patients. We have… (More)
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1990
1990
A selective inhibitor of aromatase is widely sought for the treatment of postmenopausal women with breast cancer. CGS 16949A has… (More)
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1989
1989
The effects of R 76713, a new triazole derivative, on rat ovarian, testicular and adrenal steroidogenesis were investigated both… (More)
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