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Steroid 16-alpha-Hydroxylase

Known as: Steroid 16alpha-Hydroxylase, Testosterone 16 alpha Hydroxylase, Estrone 16 alpha Hydroxylase 
A liver microsomal cytochrome P450 enzyme that catalyzes the 16-alpha-hydroxylation of a broad spectrum of steroids, fatty acids, and xenobiotics in… 
National Institutes of Health

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In BloodProcess of secretionantagonists & inhibitorsaspects of radiation effects

Papers overview

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Highly Cited
2003
Highly Cited
2003
A Rational Approach to Re-engineer Cytochrome P450 2B1 Regioselectivity Based on the Crystal Structure of Cytochrome P450 2C5*
The regioselectivity for progesterone hydroxylation by cytochrome P450 2B1 was re-engineered based on the x-ray crystal structure… 
Highly Cited
1985
Highly Cited
1985
Leukotriene B4 omega-hydroxylase in human polymorphonuclear leukocytes. Partial purification and identification as a cytochrome P-450.
Human polymorphonuclear leukocytes (PMN) not only synthesize and respond to leukotriene B4 (LTB4), but also catabolize this… 
Highly Cited
1982
Highly Cited
1982
Phenotyping of cytochromes P-450 in human tissues with monoclonal antibodies.
Cytochrome P-450 (P-450)-dependent aryl hydrocarbon hydroxylase (AHHase) and 7-ethoxycoumarin deethylase (ECDEtase) in human… 
Highly Cited
1982
Highly Cited
1982
Halogenated biphenyls: molecular toxicology.
The biologic and toxic effects of polychlorinated biphenyls (PCBs) are remarkably dependent on their structure. The most toxic… 
Review
1980
Review
1980
Inhibitors of chemical carcinogens.
A diverse group of compounds inhibit the action of chemical carcinogens when administered prior to and/or simultaneously with the… 
1979
1979
Collagen biosynthesis enzymes in serum and hepatic tissue in liver disease
Abstract. Serum immunoreactive prolyl hydroxylase protein was measured in sixty‐five patients with liver disease, and liver… 
Highly Cited
1978
Highly Cited
1978
The submicrosomal localization of 3-hydroxy-3-methylglutaryl-coenzyme-A reductase, cholesterol 7alpha-hydroxylase and cholesterol in rat liver.
In order to determine the submicrosomal distribution of cholesterol 7α-hydroxylase, 3-hydroxy-3-methylglutaryl-coenzyme-A… 
Highly Cited
1977
Highly Cited
1977
Characterization of benzo(a)pyrene hydroxylase of trout liver.
Trout liver microsomes contained as 0.40 nmole of cytochrome P-450 per mg of protein and a NADPH-cytochrome c reductase activity… 
Highly Cited
1976
Highly Cited
1976
Binding of metabolically activated benzo(a)pyrene to nuclear macromolecules.
The binding of metabolically activated [3H]benzo(a)pyrene ([3H]BP) to the DNA, RNA, histones, and nonhistones of isolated rat… 
Highly Cited
1972
Highly Cited
1972
Stimulation of cholesterol 7 -hydroxylase by phenobarbital in two strains of rats.
The effect of phenobarbital administration on the in vitro activity of cholesterol 7alpha-hydroxylase was investigated in two… 
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