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Src Homology 2 Domain-Containing, Transforming Protein 2

Known as: SHC2 Protein, Src Homology 2 Domain Containing, Transforming Protein 2, Src Homology 2 Domain-Containing-Transforming Protein C2 
An SHC-signaling adaptor protein that links GROWTH FACTOR RECEPTORS to SIGNAL TRANSDUCTION PATHWAYS in neurons.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Myhre syndrome (MIM 139210) is a developmental disorder characterized by short stature, short hands and feet, facial dysmorphism… Expand
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Highly Cited
2012
Highly Cited
2012
Background: Formin FH1 domains deliver subunits to actin filament barbed ends. Results: The transfer rate of formin Bni1p depends… Expand
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Highly Cited
2011
Highly Cited
2011
Background: The SUN domain mediates mechanical linkage across the nuclear envelope. Results: The structure of the SUN2 protein… Expand
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Highly Cited
2006
Highly Cited
2006
Phox homology (PX) domains, which have been identified in a variety of proteins involved in cell signaling and membrane… Expand
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2006
2006
Diaphanous related formins (DRFs) are cytoskeleton remodeling proteins that mediate specific upstream GTPase signals to regulate… Expand
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Highly Cited
2005
Highly Cited
2005
Formin proteins are key regulators of eukaryotic actin filament assembly and elongation, and many species possess multiple formin… Expand
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Highly Cited
2005
Highly Cited
2005
The conserved formin homology 2 (FH2) domain nucleates actin filaments and remains bound to the barbed end of the growing… Expand
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Highly Cited
2002
Highly Cited
2002
The glutamate receptor δ2 (GluRδ2) subunit is selectively expressed in cerebellar Purkinje cells and plays an important role in… Expand
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Highly Cited
2000
Highly Cited
2000
The Dbl family guanine-nucleotide exchange factors (GEFs) for Rho GTPases share the structural array of a Dbl homology (DH… Expand
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Highly Cited
1992
Highly Cited
1992
The binding of cytoplasmic signaling proteins such as phospholipase C-gamma 1 and Ras GTPase-activating protein to… Expand
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