Src Homology 2 Domain-Containing, Transforming Protein 2
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Myhre syndrome (MIM 139210) is a developmental disorder characterized by short stature, short hands and feet, facial dysmorphism… Expand Background: The SUN domain mediates mechanical linkage across the nuclear envelope. Results: The structure of the SUN2 protein… Expand Phox homology (PX) domains, which have been identified in a variety of proteins involved in cell signaling and membrane… Expand Diaphanous related formins (DRFs) are cytoskeleton remodeling proteins that mediate specific upstream GTPase signals to regulate… Expand The conserved formin homology 2 (FH2) domain nucleates actin filaments and remains bound to the barbed end of the growing… Expand Formin proteins are key regulators of eukaryotic actin filament assembly and elongation, and many species possess multiple formin… Expand The glutamate receptor δ2 (GluRδ2) subunit is selectively expressed in cerebellar Purkinje cells and plays an important role in… Expand The Dbl family guanine-nucleotide exchange factors (GEFs) for Rho GTPases share the structural array of a Dbl homology (DH… Expand A novel member of the Formin/Diaphanous family of proteins was cloned and characterized. A 4kB mRNA is ubiquitously expressed but… Expand The binding of cytoplasmic signaling proteins such as phospholipase C-gamma 1 and Ras GTPase-activating protein to… Expand