Sphingolipid Activator Proteins

Known as: Sphingolipid Activator Proteins [Chemical/Ingredient] 
A family of glycoprotein cofactors that are required for the efficient catabolization of SPHINGOLIPIDS by specific acid hydrolases such as… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1986-2017
02419862017

Papers overview

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Highly Cited
2003
Highly Cited
2003
Most soluble lysosomal proteins bind the mannose 6-phosphate receptor (M6P-R) to be sorted to the lysosomes. However, the… (More)
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2001
2001
The lysosomal degradation of ceramide is catalyzed by acid ceramidase and requires sphingolipid activator proteins (SAP) as… (More)
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2001
2001
The lysosomal degradation of ceramide is catalyzed by acid ceramidase and requires sphingolipid activator proteins (SAP) as… (More)
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1999
1999
The epidermal permeability barrier is maintained by extracellular lipid membranes within the interstices of the stratum corneum… (More)
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1998
1998
Sphingolipid activator proteins (SAPs) A to D are lysosomal factors required in degradation of sphingolipids with short… (More)
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1995
1995
The molecular defects underlying neuronal ceroid-lipofuscinoses (NCL) are still unknown. However, more data exist on the… (More)
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1995
1995
The storage material isolated from the brains of patients with infantile neuronal ceroid-lipofuscinosis (INCL) contains, on… (More)
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1995
1995
The neuronal ceroid-lipofuscinoses constitute an important group of progressive encephalopathies leading to severe psychomotor… (More)
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1994
1994
Two exo-beta-galactosidases are involved in the lysosomal degradation of glycosphingolipids: GM1-beta-galactosidase (EC 3.2.1.23… (More)
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1986
1986
Sphingolipid activator proteins (SAP) are relatively small molecular weight proteins that stimulate the enzymatic hydrolysis of… (More)
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