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Sphingolipid Activator Proteins

Known as: Sphingolipid Activator Proteins [Chemical/Ingredient] 
A family of glycoprotein cofactors that are required for the efficient catabolization of SPHINGOLIPIDS by specific acid hydrolases such as… Expand
National Institutes of Health

Papers overview

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Review
2005
Review
2005
Sphingolipids and glycosphingolipids are membrane components of eukaryotic cell surfaces. Their constitutive degradation takes… Expand
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2004
2004
The molecular defects underlying neuronal ceroid-lipofuscinoses (NCL) are still unknown. However, more data exist on the… Expand
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2003
2003
The physiological degradation of several membrane-bound glycosphingolipids (GSLs) by water-soluble lysosomal exohydrolases… Expand
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Highly Cited
2001
Highly Cited
2001
The lysosomal degradation of ceramide is catalyzed by acid ceramidase and requires sphingolipid activator proteins (SAP) as… Expand
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Highly Cited
1999
Highly Cited
1999
The epidermal permeability barrier is maintained by extracellular lipid membranes within the interstices of the stratum corneum… Expand
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1996
1996
Although the neuronal ceroid-lipofuscinoses (NCLs) are often referred to as lysosomal storage disorders, information on brain… Expand
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Review
1994
Review
1994
Glycosphingolipids (GSL) are components of the outer leaflet of the plasma membrane (PM) of vertebrate tissues. Our current… Expand
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1986
1986
Sphingolipid activator proteins (SAP) are relatively small molecular weight proteins that stimulate the enzymatic hydrolysis of… Expand
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1986
1986
Sphingolipid activator proteins (SAP) are relatively low-molecular-mass proteins that stimulate the hydrolysis of specific… Expand
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1986
1986
SummarySphingolipid activator proteins (SAP) stimulate the enzymatic hydrolysis of sphingolipids. The results of biochemical… Expand
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