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Sphingolipid Activator Proteins

Known as: Sphingolipid Activator Proteins [Chemical/Ingredient] 
A family of glycoprotein cofactors that are required for the efficient catabolization of SPHINGOLIPIDS by specific acid hydrolases such as… Expand
National Institutes of Health

Papers overview

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Review
2005
Review
2005
Sphingolipids and glycosphingolipids are membrane components of eukaryotic cell surfaces. Their constitutive degradation takes… Expand
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2004
2004
The molecular defects underlying neuronal ceroid-lipofuscinoses (NCL) are still unknown. However, more data exist on the… Expand
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2004
2004
SummarySphingolipid activator proteins (SAP) stimulate the enzymatic hydrolysis of sphingolipids. The results of biochemical… Expand
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2003
2003
The physiological degradation of several membrane-bound glycosphingolipids (GSLs) by water-soluble lysosomal exohydrolases… Expand
Highly Cited
2001
Highly Cited
2001
The lysosomal degradation of ceramide is catalyzed by acid ceramidase and requires sphingolipid activator proteins (SAP) as… Expand
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Highly Cited
1999
Highly Cited
1999
The epidermal permeability barrier is maintained by extracellular lipid membranes within the interstices of the stratum corneum… Expand
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1996
1996
Although the neuronal ceroid-lipofuscinoses (NCLs) are often referred to as lysosomal storage disorders, information on brain… Expand
Review
1994
Review
1994
Glycosphingolipids (GSL) are components of the outer leaflet of the plasma membrane (PM) of vertebrate tissues. Our current… Expand
1986
1986
Sphingolipid activator proteins (SAP) are relatively small molecular weight proteins that stimulate the enzymatic hydrolysis of… Expand
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Highly Cited
1986
Highly Cited
1986
Sphingolipid activator proteins (SAP) are relatively low-molecular-mass proteins that stimulate the hydrolysis of specific… Expand