Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Spastic Paraplegia, Hereditary

Known as: HMSN V (Hereditary Motor and Sensory Neuropathy Type V), Type V, HMSN, Spastic Paraplegia-Hypertrophic Motor-Sensory Neuropathy 
A group of inherited diseases that share similar phenotypes but are genetically diverse. Different genetic loci for autosomal recessive, autosomal… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
The development of the reprogramming technology led to generation of induced Pluripotent Stem Cells (iPSC) from a variety of… Expand
  • table 1
Is this relevant?
Review
2009
Review
2009
Most mitochondrial proteins are synthesized on cytosolic ribosomes and must be imported across one or both mitochondrial… Expand
  • figure 1
  • table 1
  • table 1
  • figure 2
  • figure 3
Is this relevant?
Review
2008
Review
2008
Hereditary spastic paraplegia (HSP) describes a heterogeneous group of genetic neurodegenerative disorders in which the most… Expand
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Oligodendrocytes are critical for the development of the plasma membrane and cytoskeleton of the axon. In this paper, we show… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2002
Highly Cited
2002
SPG13, an autosomal dominant form of pure hereditary spastic paraplegia, was recently mapped to chromosome 2q24-34 in a French… Expand
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Hereditary spastic paraplegia (HSP) is characterized by progressive weakness and spasticity of the lower limbs, caused by the… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Optic atrophy type 1 (OPA1, MIM 165500) is a dominantly inherited optic neuropathy occurring in 1 in 50,000 individuals that… Expand
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • figure 4
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Autosomal dominant hereditary spastic paraplegia (AD-HSP) is a group of genetically heterogeneous neurodegenerative disorders… Expand
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Autosomal dominant hereditary spastic paraplegia (AD-HSP) is a genetically heterogeneous neurodegenerative disorder characterized… Expand
  • figure 1
  • table 1
  • table 2
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Different regions of the brain must communicate with each other to provide the basis for the integration of sensory information… Expand
  • figure 1
  • figure 2
Is this relevant?