Spastic Paraplegia, Hereditary

Known as: HMSN V (Hereditary Motor and Sensory Neuropathy Type V), Type V, HMSN, Spastic Paraplegia-Hypertrophic Motor-Sensory Neuropathy 
A group of inherited diseases that share similar phenotypes but are genetically diverse. Different genetic loci for autosomal recessive, autosomal… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
Hereditary spastic paraplegia (HSP) is a group of clinically and genetically heterogeneous neurological disorders characterized… (More)
  • figure 1
  • table 1
  • table 2
  • table 2
  • figure 2
Is this relevant?
Review
2012
Review
2012
Human voluntary movement is controlled by the pyramidal motor system, a long CNS pathway comprising corticospinal and lower motor… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
Is this relevant?
Review
2008
Review
2008
Hereditary spastic paraplegia (HSP) describes a heterogeneous group of genetic neurodegenerative disorders in which the most… (More)
Is this relevant?
Highly Cited
2008
Highly Cited
2008
Spastin, the most common locus for mutations in hereditary spastic paraplegias, and katanin are related microtubule-severing AAA… (More)
  • figure 1
  • figure 3
  • figure 2
  • figure 4
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Oligodendrocytes are critical for the development of the plasma membrane and cytoskeleton of the axon. In this paper, we show… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2003
Highly Cited
2003
The hereditary spastic paraplegias (HSPs) are genetically heterogeneous disorders characterized by progressive lower-extremity… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Troyer syndrome (TRS) is an autosomal recessive complicated hereditary spastic paraplegia (HSP) that occurs with high frequency… (More)
  • table 1
  • figure 1
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Hereditary spastic paraplegia (HSP) is characterized by progressive weakness and spasticity of the lower limbs, caused by the… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Autosomal dominant hereditary spastic paraplegia (AD-HSP) is a genetically heterogeneous neurodegenerative disorder characterized… (More)
  • figure 1
  • table 1
  • table 2
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
1981
Highly Cited
1981
In 22 families with the "pure" form of hereditary spastic paraplegia inheritance was autosomal dominant in 19 and autosomal… (More)
  • figure 1
  • figure 2
  • table 2
  • table 1
  • table 3
Is this relevant?