FAQ

Somatotropin-Releasing Hormone

Known as: Growth Hormone Releasing Factor 44, Growth Hormone Releasing Factor, GRF 1-44 
This protein belongs to the glucagon family and is a preproprotein that is produced in the hypothalamus. The preproprotein is cleaved to form a 44 aa… (More)

Topic mentions per year

Topic mentions per year

1952-2017
05010019522016

Related topics

Related topics

29 relations

Narrower (5)

AKL-0707CJC-1295Human Pancreatic Growth Hormone-Releasing FactorJI-38
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GHRH geneGHRH wt AlleleGrowth HormoneGrowth Hormone Releasing Hormone Measurement
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Broader (3)

HormonesHypothalamic HormonesNeuropeptides

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Somatotropin-Releasing Hormone
physiological aspects
agonists
Hypothalamic structure
Neuropeptides
Hormones

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Balance in ghrelin and leptin plasma levels in anorexia nervosa patients and constitutionally thin women.
Ghrelin, a 28-amino acid octanoylated peptide, has recently been identified in rat stomach as an endogenous ligand for the GH… (More)
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Highly Cited
2002
Highly Cited
2002
The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats.
BACKGROUND & AIMS Visceral sensory information is transmitted to the brain through the afferent vagus nerve. Ghrelin, a peptide… (More)
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Highly Cited
2002
Highly Cited
2002
Disruption of PC1/3 expression in mice causes dwarfism and multiple neuroendocrine peptide processing defects.
The subtilisin-like proprotein convertases PC1/3 (SPC3) and PC2 (SPC2) are believed to be the major endoproteolytic processing… (More)
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Highly Cited
2001
Highly Cited
2001
Endocrine activities of ghrelin, a natural growth hormone secretagogue (GHS), in humans: comparison and interactions with hexarelin, a nonnatural peptidyl GHS, and GH-releasing hormone.
An endogenous ligand for the GH secretagogue-receptor (GHS-receptor) has recently been isolated, from both the rat and the human… (More)
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Highly Cited
2001
Highly Cited
2001
A low dose of ghrelin stimulates growth hormone (GH) release synergistically with GH-releasing hormone in humans.
The synergistic relationship between GH-releasing secretagogue (GHS) and GH-releasing hormone (GHRH) with respect to GH secretion… (More)
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Highly Cited
1998
Highly Cited
1998
Leptin receptor immunoreactivity in chemically defined target neurons of the hypothalamus.
The adipose tissue-derived hormone leptin regulates body weight homeostasis by decreasing food intake and increasing energy… (More)
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Highly Cited
1997
Highly Cited
1997
Distribution of mRNA encoding the growth hormone secretagogue receptor in brain and peripheral tissues.
Growth hormone release is under tight control by two hypothalamic hormones: growth hormone-releasing hormone and somatostatin. In… (More)
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Highly Cited
1993
Highly Cited
1993
Expression cloning of a human corticotropin-releasing-factor receptor.
Corticotropin-releasing factor (CRF) is the principal neuroregulator of the hypothalamic-pituitary-adrenocortical axis and plays… (More)
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Highly Cited
1993
Highly Cited
1993
Molecular basis of the little mouse phenotype and implications for cell type-specific growth.
The molecular basis for the little (lit) mouse phenotype, characterized by a hypoplastic anterior pituitary gland, is the… (More)
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Highly Cited
1992
Highly Cited
1992
Pit-1-dependent expression of the receptor for growth hormone releasing factor mediates pituitary cell growth.
In Snell (dw) and Jackson (dwJ) dwarf mice, mutations in the gene encoding Pit-1, a tissue-specific POU-domain transcription… (More)
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